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antibacterial Archives

Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Slight chemical change may improve TB treatments: study

Feb. 11, 2016—One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.

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Dynamics of a drug resistance transporter

Feb. 5, 2016—Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance.

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Studies outline new model for staph bone infections

Jun. 20, 2013—Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.

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Bacterial resistance breaks bridges

Mar. 14, 2013—Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs.

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