Aliquots
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Urine biomarker for colon cancer?
A molecule detectable in urine may be helpful in diagnosing colon cancer. Read MoreMar 10, 2012
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Combo combats dizziness
Some patients may need a combo of medications to combat a condition that causes dizziness. Read MoreMar 9, 2012
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Reversing lipid woes in cystic fibrosis
Abnormal levels of fatty acids in the blood and tissues of patients with cystic fibrosis may be reversed by supplementation with the fatty acids DHA and EPA. Read MoreMar 3, 2012
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‘Detangler’ binds, bends and cuts DNA
New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents. Read MoreMar 2, 2012
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‘Acid test’ for cervical cancer
An inexpensive, low-tech test for cervical cancer may be a good option for screening for the disease among HIV-infected women in developing countries. Read MoreFeb 21, 2012
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Stem cells take heart
Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle. Read MoreFeb 20, 2012
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Memory intact in early psychosis
Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read MoreFeb 16, 2012
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On the tail of RSV infection mechanism
New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly. Read MoreFeb 15, 2012
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Matchmaker for clinical studies
ResearchMatch.org is a web-based registry that is connecting participants and researchers for clinical studies. Read MoreFeb 8, 2012
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Tool finds connections in genome data
A new analytical tool points to genes that act together to increase disease risk. Read MoreFeb 8, 2012
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Treatment window for genetic disorder
Treatment with a drug used to prevent organ rejection partially reverses the course of tuberous sclerosis, research in mice suggests. Read MoreFeb 1, 2012
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Drugs reverse lung cancer cell changes
Drugs that target “epigenetic” changes may help treat or slow the progression of lung cancer. Read MoreFeb 1, 2012
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Protein repairs esophageal DNA damage
A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer. Read MoreJan 25, 2012
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Alcohol’s molecular mediators
Therapeutic agents focusing on the brain region involved in stress-induced relapse may be effective in preventing relapse in patients with alcohol use disorders. Read MoreJan 23, 2012
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Pumping up the pancreas in pregnancy
A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications. Read MoreJan 20, 2012
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Obesity genes linked to uterine cancer
In addition to body mass index, genetic markers of obesity may provide value in predicting endometrial cancer risk. Read MoreJan 20, 2012
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Fishing for heart attack repair tools
Managing myocardial infarction – and the resulting heart failure – remains a clinical challenge. To search for chemicals that can stimulate cardiac muscle cell production, Vanderbilt Institute of Chemical Biology investigators led by Tao Zhong, Ph.D., Terri Ni, Ph.D., and Eric Rellinger, M.D., turned to a novel drug discovery tool:… Read MoreJan 5, 2012
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Clues to flattened faces
Images of individuals with Alagille syndrome (National Institutes of Health) Mutations in the Jagged1 gene cause Alagille syndrome, an inherited disorder that affects the liver, heart, kidneys and facial structure. Patients with Alagille syndrome often have a prominent forehead, a flattened midface and a prominent chin; some have a cleft… Read MoreJan 5, 2012
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Meds’ benefits differ in dialysis patients
About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to… Read MoreJan 5, 2012
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Green tea totals colorectal cancer
Tea and its phytochemical constituents have demonstrated anti-cancer properties in cell and animal experiments – particularly green tea, which has higher levels of antioxidant polyphenols than other types of tea. iStockphoto.com Gong Yang, M.D., MPH, and colleagues evaluated the association between green tea consumption and colorectal cancer risk in participants… Read MoreJan 5, 2012