Aliquots

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes. Read More

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development. Read More

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy. Read More

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen. Read More

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors. Read More

The factor IRF6 plays important roles in the development of the tongue. Read More

Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies. Read More

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read More

An ultrasound count of potentially egg-producing follicles could predict the timing of menopause. Read More

Individuals with overexpression of the gene MECP2 have core features of autism spectrum disorder. Read More

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read More

Researchers have found an unusual interaction between a factor that “turns on” protein synthesis and one that produces fatty acids. Read More

Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer. Read More

Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin. Read More

It’s possible to cure Chagas disease – a deadly tropical infection transmitted by “kissing bugs” – in a mouse model. Read More

A protein that connects cells together participates in the calcification that occurs in heart valve disease. Read More

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance. Read More

The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development. Read More

An unexpected group of cells generates the coronary arteries and may be useful for regeneration therapies following injury to the heart. Read More

The kidney can mediate its own repair through proliferation of resident immune system cells. Read More