Aliquots
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Autism narrows brain’s reward response
MRI brain scans reveal that children with autism spectrum disorders respond to a narrower range of familiar rewards. Read MoreNov 27, 2013
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Mitochondrial mutations not random
A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues. Read MoreNov 25, 2013
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What makes us human?
Using computational tools to search for the genetic basis of what makes us human, Vanderbilt Assistant Professor of Biomedical Informatics Tony Capra and colleagues at the University of California-San Francisco have identified promising candidate regions. Read MoreNov 22, 2013
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Therapeutic target for synovial sarcoma
Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read MoreNov 21, 2013
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Amish aid study of Parkinson genetics
Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles. Read MoreNov 11, 2013
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Defusing ‘C. diff’ infection
Clostridium difficile on the intestinal lining. (Wellcome Images) Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. Read MoreNov 8, 2013
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Neurotransmitter’s role in bone balance
Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling. Read MoreNov 7, 2013
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Preserving antibiotic arsenal for TB
Clinicians should be cautious about prescribing newer fluoroquinolone antibiotics to patients with TB risk factors; doing so may jeopardize the use of these agents against TB. Read MoreOct 30, 2013
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Tool predicts risk for developmental delays in early childhood
A non-invasive measure of electrical brain activity in preterm infants predicts cognitive and communication functioning during early childhood, according to a new Vanderbilt University study. Read MoreOct 28, 2013
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Targets of SIN drive cell division
Vanderbilt researchers have identified a key regulator of cell division. Read MoreOct 25, 2013
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Shining a light on night blindness
Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness. Read MoreOct 24, 2013
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Relaxin combats insulin resistance
The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance. Read MoreOct 16, 2013
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Magnesium impacts vitamin D status
Magnesium and vitamin D appear to work together to reduce risk of death from cardiovascular disease and colorectal cancer. Read MoreOct 14, 2013
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New target for stopping inflammation
Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases. Read MoreOct 11, 2013
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Probing mutant EGF receptor regulation
Understanding the regulation of mutant EGF receptors commonly found in lung cancers could lead to new targeted therapies. Read MoreOct 10, 2013
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Early cell death in MS
Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis. Read MoreOct 2, 2013
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Gene interactions and cavities
Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay. Read MoreSep 30, 2013
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Metabolic profiling of vision loss
A panel of metabolites – small molecules that are part of metabolic processes – that are unique to macular degeneration will shed light on the disease and aid diagnosis. Read MoreSep 27, 2013
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Cell changes en route to stomach cancer
Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read MoreSep 26, 2013