Aliquots

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer. Read More

The antioxidant vitamin E prevented the buildup of toxic products in a model of a rare genetic disorder, suggesting new strategies for therapeutic development. Read More

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity. Read More

A new computational model of the interactions between vocal folds and the air around them could aid in designing new treatments for voice disorders. Read More

Understanding the relationship between the thinning and rupture of fetal membranes and the presence of bacteria could lead to treatment and prevention strategies for premature birth. Read More

by Denise Anthony (iStock) A Vanderbilt University-led research team has solved a long-standing riddle: Why do people of mostly Amerindian ancestry in the Andes have a gastric cancer rate that is 25 times higher than that of fellow Colombians of mostly African descent only 124 miles away on the coast?… Read More

Understanding how HIV infection affects immune system B cells may guide strategies for vaccine development. Read More

Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes. Read More

Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception. Read More

An association between rigid-compulsive behaviors and gastrointestinal symptoms in autism spectrum disorder may point to a common biological pathway that impacts both the brain and the gut. Read More

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies. Read More

The breast cancer drug tamoxifen improves cognitive performance in post-menopausal women. Read More

The protein CK1 delays cell division to avoid the generation of defects that drive tumorigenesis. Read More

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read More

MRI brain scans reveal that children with autism spectrum disorders respond to a narrower range of familiar rewards. Read More

A study of mitochondrial DNA mutations suggests they result from a process that selects for particular mutations in certain tissues. Read More

Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer. Read More

Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read More

Amish populations are valuable for genetic research because of their isolation, shared ancestry and homogeneous lifestyles. Read More

Clostridium difficile on the intestinal lining. (Wellcome Images) Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. Read More