Aliquots

The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells. Read More

A combination of two types of therapy may be more effective in treating castration-resistant prostate cancer. Read More

A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection. Read More

Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease. Read More

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants. Read More

Certain antibiotics increase the risk of a congenital heart disorder called patency of the ductus arteriosis. Read More

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered. Read More

Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies. Read More

The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis. Read More

A non-invasive imaging tool could test potential cancer therapies quickly to personalize therapy for patients. Read More

Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures. Read More

A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies. Read More

Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis. Read More

Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads. Read More

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies. Read More

Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way. Read More

A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1. Read More

A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options. Read More

Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration. Read More

It may be possible to use skin cells as biomarkers to diagnose and manage depression. Read More