Aliquots
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Neuronal culprit in genetic disease
A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered. Read MoreOct 14, 2014
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Aspirin and allergies
Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies. Read MoreOct 10, 2014
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Long-range signaling to stem cells
The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis. Read MoreOct 9, 2014
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Optical imaging in drug therapy screens
A non-invasive imaging tool could test potential cancer therapies quickly to personalize therapy for patients. Read MoreOct 1, 2014
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Seizure mutation impairs receptor
Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures. Read MoreSep 30, 2014
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Biomarker for diabetic eye disease
A person’s mitochondrial gene “signature” could predict risk for diabetic retinopathy and guide early intervention strategies. Read MoreSep 26, 2014
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A path to sarcoidosis treatment
Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis. Read MoreSep 25, 2014
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Dioxin, fathers and preterm birth
Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads. Read MoreSep 18, 2014
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Patient-derived stem cells shed light on pulmonary hypertension
Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies. Read MoreSep 16, 2014
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Schizophrenia ‘switches’ discovered
Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way. Read MoreSep 12, 2014
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Bone healing therapy for NF1 fractures
A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1. Read MoreSep 11, 2014
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Aggressive bone cancers build more blood vessels
A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options. Read MoreSep 3, 2014
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Protein interaction protects against neurodegeneration
Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration. Read MoreSep 2, 2014
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Skin biopsy to diagnose depression?
It may be possible to use skin cells as biomarkers to diagnose and manage depression. Read MoreAug 29, 2014
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Limiting breast cancer metastasis
Vanderbilt researchers have identified a new target for blocking breast cancer metastasis. Read MoreAug 28, 2014
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Enzyme holds the door for influenza
Compounds developed at Vanderbilt University may offer a new way to block influenza infection. Read MoreAug 20, 2014
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Keeping an eye on blast trauma
Understanding the cellular and molecular responses of the eye to blast injury could guide new treatment development. Read MoreAug 19, 2014
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Weight regain after gastric bypass
Early weight regain after gastric bypass surgery does not reverse metabolic improvements, and the "hunger hormone" ghrelin might indicate who is susceptible to weight regain. Read MoreAug 15, 2014
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Growth factor blockade targets breast tumors
Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis. Read MoreAug 14, 2014
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Low selenium and lung cancer
Vanderbilt researchers have found that selenium deficiency may contribute to the racial disparity in lung cancer incidence. Read MoreAug 6, 2014