Aliquots

  • Vanderbilt University

    Healing without scarring

    Drugs that inhibit the Wnt signaling pathway can regenerate injured skin and may be useful in treating fibromatosis, degenerative joint disease and cancer. Read More

    Oct 16, 2015

  • iStock

    Risk of death in the ICU

    The irregular heart rhythm atrial fibrillation increases the risk of death in patients in the intensive care unit. Read More

    Oct 15, 2015

  • aspergillus culture

    Rational design of novel antifungals

    Structural and molecular details of an anti-fungal target's interaction with inhibitors suggest ways to design better treatments for fungal infections. Read More

    Oct 7, 2015

  • x-ray of lungs with a suspicious spot highlighted in red

    Potential target for lung cancer therapy

    The glutamine transporter protein appears to contribute to the survival of lung cancer cells, suggesting it may be a useful diagnostic biomarker and target for therapies. Read More

    Oct 5, 2015

  • Vanderbilt University

    The yin and yang of COX-2

    New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs. Read More

    Oct 2, 2015

  • conceptual - glowing cell

    Tolerating a transplant

    A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease. Read More

    Oct 1, 2015

  • Vanderbilt University

    Data diving for health

    To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases. Read More

    Sep 23, 2015

  • Vanderbilt University

    Keep your coat on, virus!

    A compound acting on serotonin receptors delays a critical step during reovirus cell entry, reducing viral infectivity. Read More

    Sep 22, 2015

  • Vanderbilt University

    Nerve cell remodelers

    Vanderbilt investigators have defined a gene expression program that controls the timing of synaptic remodeling – a process that is critical to brain development, learning and memory. Read More

    Sep 18, 2015

  • Vanderbilt University

    Heart repair factor

    A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack. Read More

    Sep 17, 2015

  • Vanderbilt University

    How to build a basement

    Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer. Read More

    Sep 9, 2015

  • Vanderbilt University

    Immune cells and obesity

    Understanding how macrophage immune cells accumulate in fat tissue and contribute to the pathology of obesity could lead to the development of novel therapeutics for metabolic disorders. Read More

    Sep 8, 2015

  • Vanderbilt University

    Vitamin C protects blood vessel lining

    Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases. Read More

    Sep 4, 2015

  • Vanderbilt University

    Bad “traffic” linked to cancer

    Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers. Read More

    Sep 3, 2015

  • Vanderbilt University

    Framework for studying cell responses

    Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease. Read More

    Aug 26, 2015

  • Vanderbilt University

    How the cell makes morphine

    Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine. Read More

    Aug 25, 2015

  • Vanderbilt University

    Brain circuitry in psychosis

    Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More

    Aug 21, 2015

  • Vanderbilt University

    New therapeutic target for diabetes

    The factor FoxM1 increases the proliferation and function of insulin-producing beta cells, making it an attractive therapeutic target for diabetes. Read More

    Aug 20, 2015

  • Neurons

    Origins of neuroblastoma

    Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer. Read More

    Aug 12, 2015

  • Vanderbilt University

    Drug combos enhance ovarian cancer cell death

    Drugs that target DNA damage improve ovarian cancer cell response to platinum chemotherapies, suggesting new therapeutic opportunities. Read More

    Aug 11, 2015