Aliquots

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read More

Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role. Read More

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies. Read More

Vanderbilt researchers report a structure of a human metabolic enzyme bound to its substrate 17alpha-hydroxyprogesterone. Read More

The hormone erythropoietin (Epo) controls red blood cell production and synthetic forms of Epo treat multiple disorders. New Vanderbilt research details how Epo works. Read More

Vanderbilt researchers have found that non-coding regions of the genome appear to contribute to the risk of autoimmune diseases and may represent attractive therapeutic targets. Read More

Signaling through a complex of proteins called mTORC2 plays a role in breast cancer migration, invasion and metastasis, Vanderbilt researchers reported. Read More

Bile acids produced by a western diet alter the composition of the gut microbiota and promote intestinal carcinogenesis. Read More

The identification of a genetic culprit for hypoplastic left heart syndrome could lead to new treatments for the condition. Read More

A signaling molecule called interleukin-6 may be a therapeutic target to prevent vision loss or nerve degeneration in glaucoma, Vanderbilt researchers have discovered. Read More

Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans. Read More

A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer. Read More

A PET probe that detects the amino acid glutamine predicts whether tumors respond to certain targeted therapies in preclinical animal models. Read More

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away. Read More

Vanderbilt investigators report that dysregulation of certain immune cells in the intestines may lead to inflammation and disease. Read More

Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development. Read More

Blood type A was associated with longer ovarian cancer survival in a recent Vanderbilt-led study. Read More

RSV infection reduces the risk of infection with human rhinovirus, which could have implications for vaccine development and prevention strategies for viral respiratory tract infections in infants. Read More

Interventions that increase circulating levels of compounds called EETs may improve insulin sensitivity and treat hypertension. Read More

Vanderbilt investigators have identified novel regulators of insulin-producing beta-cell proliferation and survival, suggesting new targets for the treatment of type 2 diabetes. Read More