Health And Medicine

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read More

A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation. Read More

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read More

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented. Read More

An international research team led by scientists from Vanderbilt University Medical Center has identified a genetic variant that protects people with HIV from developing active tuberculosis. The variant is near the gene encoding the infection-fighting cytokine IL-12. Read More

Drinking a high carbohydrate shake can have an acute and detrimental effect on heart function, a study published in the Journal of the American College of Cardiology (JACC) has found. Read More

Biomarker tests that help determine which patients may benefit from molecularly targeted therapies need better evidence and oversight to improve their effectiveness and availability, according to a study by the Institute of Medicine (IOM) of the National Academies of Sciences, Engineering, and Medicine. Read More

Pioneering Vanderbilt diabetes researcher Charles R. “Rollo” Park, M.D., celebrated his 100th birthday on March 2 at the Heritage of Brentwood with his wife of more than 70 years, Jane Park, Ph.D., professor emerita of Molecular Physiology and Biophysics. Read More

A new animal model can be used to “dissect” the inflammatory response to infection. Read More

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read More

Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat. Read More

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More

Researchers at Vanderbilt University Medical Center have relieved symptoms in a mouse model of Rett syndrome with a drug-like compound that works like the dimmer switch in an electrical circuit. Read More

Mother-to-child transmission of the human immunodeficiency virus (HIV), which causes AIDS, is still a major problem in resource-limited, rural areas of the world where health care providers are scarce. Read More

Vanderbilt University Medical Center and Brigham and Women’s Hospital in Boston recently collaborated on a study analysis to determine the effect of a tailored, pharmacist-delivered health literacy intervention on unplanned hospital readmission or emergency department visit following discharge. Read More

Aron Parekh, Ph.D., assistant professor of Otolaryngology, has received a four-year, $790,000 Research Scholar Grant from the American Cancer Society to further his research into the mechanical and biological properties of cancer cells and the methods by which they leave the initial tumor and spread or metastasize to other parts of the body. Read More

Vanderbilt graduate students demonstrated that they can summarize their 80,000-word theses in less than three minutes using terms that members of the public can understand during this year's Three Minute Thesis competition. Read More

C. Michael Stein, MBChB., and his colleagues at Vanderbilt University Medical Center have received a five-year, $1.35 million award from the Arthritis Foundation to develop new biomarkers for rheumatoid arthritis that also may revolutionize treatment. Read More

A multicenter study led by Vanderbilt University Medical Center (VUMC) investigators found that pancreatic cancer patients who underwent surgery and received chemotherapy lived longer and had fewer cancer recurrences in other parts of the body than patients who also received chemoradiation therapy. Read More