Health And Medicine
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Delirium, benzos and the pediatric ICU
With other risk factors held equal, children who received a benzodiazepine sedative drug were nearly three times more likely to experience delirium – confused thought – the following day. Read MoreOct 2, 2017
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Novel insights to antibiotic targets
New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines. Read MoreSep 29, 2017
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Cellular calcium handling in diabetes
Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health. Read MoreSep 28, 2017
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VICC investigators land support from Komen Foundation
Three breast cancer investigators from Vanderbilt-Ingram Cancer Center (VICC) have been awarded research grants from Susan G. Komen, a nonprofit foundation devoted to supporting cancer research, community health outreach, advocacy and public policy initiatives. Read MoreSep 28, 2017
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Excess dietary manganese increases risk of staph infection in heart
Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”). Read MoreSep 21, 2017
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Pancreatic islets study may spur diabetes treatment advances
Investigators in the Vanderbilt Diabetes Research and Training Center (VDRTC) and collaborators at Stanford University have discovered new insights into the molecular mechanisms of cell proliferation in juvenile human pancreatic islets, information that could lead to new treatments for diabetes. Read MoreSep 21, 2017
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VUSN names Kleinpell assistant dean for Clinical Scholarship
Ruth Kleinpell, Ph.D., R.N., an internationally recognized nurse researcher, scholar and educator, has joined Vanderbilt University School of Nursing (VUSN) as assistant dean for Clinical Scholarship and professor of Nursing. Read MoreSep 21, 2017
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Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs
An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy. Read MoreSep 20, 2017
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Unique premed program teaches new approach to race and health
A premed program that teaches undergraduates about institutional racism is up and coming at Vanderbilt Read MoreSep 20, 2017
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NSAIDs, genetics and miscarriage
A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage. Read MoreSep 20, 2017
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Medication safety in the ICU
Facilitated reporting of medication-related events in the intensive care unit can provide opportunities for optimizing quality of care and patient safety. Read MoreSep 19, 2017
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Inhibiting obesity
An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain. Read MoreSep 15, 2017
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Acid reflux cancer link
Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer. Read MoreSep 14, 2017
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Piano named to lead School of Nursing research program
Mariann Piano, Ph.D., a distinguished researcher in cardiovascular disease and expert on the effects of binge drinking and young adults, has been named senior associate dean for Research at Vanderbilt University School of Nursing (VUSN). Read MoreSep 14, 2017
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Heat a trigger for seizures
Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation. Read MoreSep 6, 2017
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Pain and Alzheimer’s disease
Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked. Read MoreSep 5, 2017
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Restricting HIV-1 infection
Vanderbilt researchers are discovering ways that host proteins block HIV-1 infection, which could suggest new avenues for treatment. Read MoreSep 1, 2017
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Pancreatic cancer development
Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read MoreAug 31, 2017
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Study seeks to streamline validation of EHR data
Vanderbilt University Medical Center has been approved for a $1 million funding award by the Patient-Centered Outcomes Research Institute (PCORI) to study more efficient and feasible ways to validate electronic health records (EHR) and incorporate this information into medical studies. Read MoreAug 31, 2017
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End-stage kidney disease study seeks to delay dialysis
Vanderbilt University Medical Center (VUMC) is studying the safety of a possible treatment for diabetic kidney disease that would delay or prevent the need for kidney replacement such as dialysis. Read MoreAug 31, 2017