Health And Medicine

Pulmonary hypertension may be treated by targeting a bone marrow cell that normally promotes the growth of new blood vessels, according to new research by David Merryman. Read More

Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to new research by Lindsay Mayberry and Sunil Kripalani. Read More

Susan Wente and Laura Glass have developed an experimental cell culture model system to investigate the link between stress granules and cell resistance to toxic stress, which could lead to new avenues for treating cancer treatment resistance. Read More

Fiona Harrison and colleagues have found evidence that Vitamin C can help protect brains against seizures and cognitive decline in Alzheimer’s disease. Read More

Rebecca Sappington and colleagues have found that increasing cGMP — part of a signaling pathway that was previously found to regulate intraocular pressure — protects retinal ganglion cells affected by glaucoma. Read More

Lin Zhu and Rob Stafford have found that obesity interferes with cholesterol-improving CTEP inhibitors. Read More

Jeffrey Rathmell and colleagues show that a drug that inhibits glutamine metabolism — currently in clinical trials as an anticancer agent — might also be useful as a treatment for inflammatory and autoimmune diseases. Read More

Vanderbilt researchers led by Buddy Creech are searching for the key to lasting protection against influenza by examining naturally protecting cells found in bone marrow. Read More

The grant will allow Charles Caskey to lead research into using ultrasound as an image-guided therapy for drug delivery. Read More

The grant will allow Kennedy Center researchers to analyze data from VUMC's Synthetic Derivative and BioVU databanks to study biomarkers associated with Down Syndrome. Read More

A new link between a support protein within the brain's white matter and known Alzheimer's biomarkers discovered by Angela Jefferson and colleagues bring researchers a step toward earlier and more precise detection of neuropathology underlying cognitive impairment that may lead to new targeted therapies Read More

Vanderbilt chemists have been awarded $7.2 million over the next five years from the National Cancer Institute to lead an initiative to better understand how a combination chemotherapy for breast cancer targets DNA. Read More

Raymond Harris, Ming-Zhi Zhang and colleagues suggest pathways activated by the epidermal growth factor receptor may be promising targets for treating diabetic kidney disease. Read More

New findings by Dawn Newcomb and colleagues suggest an explanation for why women are more prone to asthma than men. Read More

Research led by Sanjay Mishra, and colleagues suggests modular sHSP architecture contributes to the ability of heat-protective proteins to serve as chaperones for a range of unfolded proteins. Read More

Reducing nitric oxide helps insulin move more quickly through blood vessels, find David Wasserman and colleagues. Read More

Bradley Malin, professor of biomedical informatics, biostatistics and computer science, is among 85 newly elected members of the National Academy of Medicine. Read More

Loss of a protein that regulates mitochondrial function can greatly increase the risk of a heart attack, report Eric Gamazon, Sandra Zinkel and graduate students Christie Salisbury-Ruf and Clinton Bertram in new research. Read More

The hidden lives of medical biomarkers are the focus of a recent study in Nature Communications by Jonathan Mosley. Read More

New research by Alyssa Hasty and colleagues shows that a certain immune cell can absorb excess iron that can compromise healthy fat tissue. Read More