Health And Medicine
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Signals from the “conveyor belt”
Carlos Lopez, Tina Iverson and Vsevolod Gurevich propose that a conveyer belt best describes the mechanism by which cellular signals are handed off from enzyme to enzyme in the brain. Read MoreJan 18, 2019
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Building a pancreas
Ken Lau and Guoqiang Gu have identified a critical biomarker in determining how a pancreatic progenitor cell will develop. Read MoreJan 17, 2019
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Study points to alternate therapy for rare form of diabetes
An unexpected finding by Rachana Haliyur during the cellular analysis of human pancreatic tissue has revealed new information about a rare type of diabetes and underscores the importance of genetic testing for some individuals diagnosed with type 1 diabetes. Read MoreJan 17, 2019
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Research explores link between stem cell transplant, diabetes
Brian Engelhardt is studying why as many as 50 percent of stem cell transplant recipients develop diabetes. Read MoreJan 17, 2019
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Pain relievers a risk for C. diff?
David Aronoff and colleagues report an increased risk of the serious gastrointestinal infection C. diff following the use of NSAID pain relievers. Read MoreJan 17, 2019
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Findings on eye-signal blending re-examine Nobel-winning research
Knowing which neurons are involved in the eye signal blending process also opens the door to targeted brain therapies that reach well beyond eye patches. Read MoreJan 17, 2019
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Team finds how error and reward signals are organized within cerebral cortex
Psychiatrists diagnose people with schizophrenia, ADHD, bipolar disorder and other mental illnesses by spending time with them, looking for the particular behavior symptoms of each. What follows can be a hit-or-miss series of medications and dosages until disruptive behaviors go away. By deciphering the circuitry of the medial frontal cortex… Read MoreJan 14, 2019
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Study identifies novel genetic factors for colorectal cancer risk
A large-scale study conducted among East Asians and led by Vanderbilt researchers has identified multiple, previously unknown genetic risk factors for colorectal cancer. Read MoreJan 10, 2019
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Bile acids mediate metabolic benefits of weight-loss surgery
A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery. Read MoreJan 10, 2019
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Lindsley named fellow of National Academy of Inventors
Craig Lindsley, co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been named a fellow of the National Academy of Inventors. Read MoreJan 4, 2019
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Hundreds of new blood pressure gene variations discovered
In one of the largest studies of its kind, an international research team led by 20 Vanderbilt University scientists has discovered more than 200 new genetic variations associated with high blood pressure. Read MoreJan 4, 2019
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Study uses IT to prevent early childhood obesity
A research team led by Russell Rothman has been approved for a $7 million research funding award from the Patient-Centered Outcomes Research Institute to conduct a trial comparing clinic and consumer information technology approaches to promote healthy behaviors and prevent early childhood obesity. Read MoreJan 4, 2019
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Vanderbilt, Boehringer Ingelheim announce partnership to develop therapies for psychiatric disorders
Boehringer Ingelheim and Vanderbilt Center for Neuroscience Drug Discovery today announced two new global agreements to investigate, develop and commercialize novel small molecules targeting two distinct G-protein coupled receptors known to engage in the modulation of certain brain circuitries, which are altered in neuropsychiatric conditions such as schizophrenia. Read MoreJan 3, 2019
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People with schizophrenia experience emotion differently from others, ‘body maps’ show
Vanderbilt University researchers are working to understand how people with schizophrenia experience emotion through their bodies. Read MoreDec 21, 2018
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Breast cancer-killing RIG
New research led by Rebecca Cook demonstrates that an antiviral receptor called RIG-I has potent immunogenic and therapeutic effects in breast cancer. Read MoreDec 19, 2018
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Using a mapping technique to reassess prior Alzheimer’s studies finds ‘powerful,’ improved reproducibility
A neural mapping approach that pegs results from more than two dozen previous Alzheimer’s studies found that reproducibility improves when trying to isolate symptoms to a brain network rather than a single area of the brain. Read MoreDec 19, 2018
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Study shows magnesium optimizes vitamin D status
A randomized trial by Vanderbilt-Ingram Cancer Center researchers indicates that magnesium optimizes vitamin D status, raising it in people with deficient levels and lowering it in people with high levels. Read MoreDec 19, 2018
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Policies for Action Research Hub at Vanderbilt created
Vanderbilt School of Medicine and Peabody College have established a transinstitutional Policies for Action Research Hub to better understand and develop recommendations to address the needs of some of Tennessee’s most vulnerable children, including those in immigrant families and with prenatal exposure to opioids. Read MoreDec 14, 2018
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Lean vs. obese adipose tissue cells
New research led by Alyssa Hasty shows that diet-induced weight loss in obese individuals increases levels of a white blood cell that promotes metabolic health in fatty tissues, but not in the liver. Read MoreDec 14, 2018
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The exocyst dynamo
Mukhtar Ahmed and colleagues say the methods they employed to understand the mechanisms by which exocysts--protein complexes essential to life--function have the potential to revolutionize our understanding of cell dynamics. Read MoreDec 14, 2018