Research
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NIH grant bolsters mass spectrometry research initiatives
The National Institutes of Health (NIH) has awarded a major renewal grant to continue the National Research Resource for Imaging Mass Spectrometry at Vanderbilt University School of Medicine. Read MoreAug 11, 2016
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Team explores transcription factor’s autoimmunity role
Increasing expression of a transcription factor called KLF2 can promote immunological self-tolerance and “tune down” autoimmunity, researchers at Vanderbilt University Medical Center reported recently. Read MoreAug 11, 2016
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Research team takes aim at Ebola virus ‘decoy protein’
Using an antibody generated at Vanderbilt University Medical Center that neutralizes the Ebola virus, researchers at the Scripps Research Institute in La Jolla, California, have determined the structure of a “decoy” protein that may enable the virus to evade detection by the immune system. Read MoreAug 11, 2016
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Transcription factor evolution
Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression. Read MoreAug 11, 2016
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Study explores low oxygen’s impact on antibody quality
Hypoxia (lack of enough oxygen) is bad for the body as a whole, but in the neighborhood where infection-fighting antibodies arise, may be important for keeping proper order. Read MoreAug 11, 2016
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Study reveals neurotransmitter glutamate’s molecular structure
Terunaga Nakagawa, with colleagues from Japan and Oxford University in England, has discovered the bridgelike molecular structure of a mysterious glutamate receptor. Read MoreAug 11, 2016
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Total number of neurons—not enlarged prefrontal region—hallmark of human brain
Research by Associate Professor of Psychology Suzana Herculano-Houzel finds that human intelligence comes from the number of neurons in our brains—and it was the invention of cooking that made neuron development possible. Read MoreAug 9, 2016
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Judaeo-Arabic culture focus of cross-disciplinary conference
Renowned experts across disciplines will speak on Judaeo-Arabic history and culture at an international conference at Vanderbilt University Aug. 15-18. Read MoreAug 9, 2016
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Using nanotechnology to give fuel cells more oomph
Researchers from Vanderbilt University have developed porous polymer-fiber electrodes that may make fuel cells more powerful. Read MoreAug 8, 2016
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HIV treatment and TB risk
Tuberculosis (TB) remains an important public health problem, particularly among people infected with the human immunodeficiency virus (HIV). Read MoreAug 4, 2016
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Kleberg Foundation grant bolsters cancer drug discovery efforts
The Robert J. Kleberg Jr. and Helen C. Kleberg Foundation has awarded a $3 million grant to Vanderbilt-Ingram Cancer Center (VICC) investigators in support of VICC’s drug discovery program. The gift awarded over the next three years from the private, San Antonio, Texas-based foundation will enable VICC researchers to pursue the development of new compounds to block the activity of cancer-causing genes and proteins that had previously been considered “undruggable.” Read MoreAug 3, 2016
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Fetal impact of antidepressants
Antidepressant use during pregnancy is common. Fetal exposure to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) is associated with the life-threatening condition PPHN (persistent pulmonary hypertension of the newborn), but a causal link has not been established. Read MoreAug 3, 2016
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Discovery of male-harming DNA mutation reinforces ‘mother’s curse’ hypothesis
There is new evidence that the "mother’s curse" – the possibility that moms may transmit genes to their children that harm their sons but not their daughters – holds true in animals. Read MoreAug 2, 2016
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Refining neural circuitry
During development, neural circuits are remodeled – some synapses are eliminated and others are strengthened – to produce a mature, functional nervous system. Read MoreAug 2, 2016
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Possible overeating antidote
The 2C-subtype of the serotonin receptor (5HT2C), which binds the neurotransmitter serotonin, plays an important role in regulating food intake and metabolism. Read MoreAug 1, 2016
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Newly discovered fossils strengthen proposition that world’s first mass extinction engineered by early animals
New fossil evidence strengthens the proposition that the world’s first mass extinction was caused by ‘ecosystem engineers’ – newly evolved organisms that radically altered the environment. Read MoreJul 29, 2016
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Award bolsters study of alcohol’s impact on the brain
Vanderbilt University researcher Danny Winder, Ph.D., has received a MERIT Award from the National Institute of Alcohol Abuse and Addiction (NIAAA), part of the National Institutes of Health, for his contributions to understanding how alcohol affects the brain. Read MoreJul 28, 2016
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Seminar focuses on latest concussion research
Neuropsychologist Gary Solomon, Ph.D., recently weighed in on one of the hottest debates in sports medicine, asserting that research doesn’t support the popular theory that concussions put athletes at higher risk for psychiatric illness. Read MoreJul 28, 2016
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Opioids’ impact on women’s health explored at research symposium
Women may be at higher risk than men when it comes to overuse of opioid-containing painkillers, speakers warned at a research symposium at Vanderbilt University Medical Center earlier this month. Read MoreJul 28, 2016
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Marrow cells’ role in pulmonary hypertension explored
Cells from the bone marrow participate in the development of pulmonary arterial hypertension (PAH), and they can also protect against it, according to new findings from a team of Vanderbilt University Medical Center investigators. Read MoreJul 28, 2016