Research

An international team of researchers led by Eric Gamazon has integrated gene expression and disease association data to better understand the biological mechanisms of complex human diseases. Read More

Robert Freundlich and colleagues analyzed records for nearly 1.2 million patients and found that, among patients who died within 30 days of surgery, one in five had a complication independently associated with mortality. Read More

In new research, Hassane Mchaourab and colleagues have uncovered new insights into drug resistance that could lead to the development of new anti-cancer and antibacterial drugs. Read More

Disruption of the integrity of the intestinal lining or epithelium contributes to a “leaky” gut and is a common feature of patients with inflammatory bowel disease. Yash Choksi, Christopher Williams and colleagues found that low levels of a certain protein exacerbated the condition. Read More

Kelsey Hatzell studied the performance of a promising electrolyte for solid-state lithium batteries under real-world conditions. Read More

In areas of the country disproportionately affected by the opioid crisis, treatment programs are less likely to accept patients paying through insurance of any type or accept pregnant women, a new Vanderbilt study found. Read More

A drug used to treat diabetes, liraglutide, may point to new therapies for respiratory syncytial virus (RSV) bronchiolitis — inflammation and obstruction of the lungs’ small airways. Read More

One of the first studies to examine the health impacts of legal marriage for LGBT individuals has found gay men were more likely to receive routine medical care following marriage legalization. Read More

New findings by Jörn-Hendrik Weitkamp and colleagues provide the first account of bacterial signatures in mammalian fetal intestinal tissue. The results suggest that bacterial DNA moves from the mother’s microbiome into the fetal intestine, which may be a critical stimulus for normal mucosal immune development. Read More

Chronic inflammation is a predisposing condition for colorectal cancer, the third leading cause of cancer-related deaths in the United States. Anna Means, Ph.D., and colleagues have now linked inflammation-driven carcinogenesis in the colon to loss of an important signaling protein called SMAD4. Read More

Appello was established with major investment from New York-based Deerfield Management, which specializes in accelerating drug development projects at universities and other nonprofits. Read More

There’s one bond that had scientists stumped: the one between some types of metals and carbon. Professor of Chemistry Timothy Hanusa set out to replicate this unique type of bond using modeling. Read More

Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease. Read More

The new factor, an enzyme involved in host-pathogen interactions, may be a viable target for treating staph infections. Read More

Vanderbilt engineers have successfully developed and validated the feasibility of blockchain-based technologies for secure, confidential sharing of patient medical records in a case study that demonstrates how blockchain could solve a huge healthcare challenge. Read More

Justus Ndukaife, who won the 2017 Chorafas Foundation Prize in Physics for his nanotweezers work, also recently was selected for the Carnegie African Diaspora Fellowship Program. Read More

The device is from the lab of Professor Michael Goldfarb, perhaps best known for working on a bionic leg with shark attack victim Craig Hutto and later developing the Indego exoskeleton. Read More

Vanderbilt economist W. Kip Viscusi says putting a price tag on the value of a person’s life makes people and products safer. Read More

Vanderbilt Professor of Law and former Treasury adviser Morgan Ricks argues that the general public, businesses and institutions should have the option to open an account at the Federal Reserve. Read More

Vanderbilt environmental researchers developed an index of city water policies and gathered data on the climate, water sources, population, economy and political leanings. Read More