Health And Medicine

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read More

Vanderbilt University Medical Center has entered into a strategic research agreement with Celgene Corporation, a biopharmaceutical company based in Summit, New Jersey. Read More

For Vanderbilt senior Ariel Helms from Oklahoma, twists and turns in her past, including a long-kept family secret, led to her passion for discovery in a Vanderbilt lab. Read More

The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility. Read More

A new clinical implementation study from Vanderbilt University Medical Center measures how physicians have responded to the introduction of routine genetic testing to predict patient response to the commonly prescribed antiplatelet drug clopidogrel. Read More

A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read More

Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires. Read More

A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read More

A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation. Read More

The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read More

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented. Read More

An international research team led by scientists from Vanderbilt University Medical Center has identified a genetic variant that protects people with HIV from developing active tuberculosis. The variant is near the gene encoding the infection-fighting cytokine IL-12. Read More

Drinking a high carbohydrate shake can have an acute and detrimental effect on heart function, a study published in the Journal of the American College of Cardiology (JACC) has found. Read More

Biomarker tests that help determine which patients may benefit from molecularly targeted therapies need better evidence and oversight to improve their effectiveness and availability, according to a study by the Institute of Medicine (IOM) of the National Academies of Sciences, Engineering, and Medicine. Read More

Pioneering Vanderbilt diabetes researcher Charles R. “Rollo” Park, M.D., celebrated his 100th birthday on March 2 at the Heritage of Brentwood with his wife of more than 70 years, Jane Park, Ph.D., professor emerita of Molecular Physiology and Biophysics. Read More

A new animal model can be used to “dissect” the inflammatory response to infection. Read More

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish. Read More

Researchers at Vanderbilt University Medical Center have isolated human antibodies against a type of bird flu that has killed more than 200 people in China since 2012 and which may pose a worldwide pandemic threat. Read More

Actin and microtubule cytoskeletons are coordinated during cytokinesis – the process that separates one cell into two and is linked to events underlying cancer. Read More

Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy. Read More