Health And Medicine
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Mechanism of a DNA repair protein
Vanderbilt investigators have discovered details about the mechanism of an important DNA repair protein that maintains genome stability. Read MoreApr 15, 2016
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Marnett named dean of basic sciences for School of Medicine
Provost and Vice Chancellor for Academic Affairs Susan R. Wente announced today that Lawrence J. Marnett will be named dean of basic sciences in the Vanderbilt University School of Medicine at the time of the legal separation of the university and Medical Center. Read MoreApr 14, 2016
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Study spots possible new approach to prevent obesity
An international research team that included scientists from Vanderbilt University Medical Center has found a novel way to counteract obesity in mice — by stimulating the growth of blood vessels in fat tissue. Read MoreApr 14, 2016
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First subject enrolled in international HIV prevention study
This month an international HIV prevention trial was launched that is testing the infection-preventing prowess of a monoclonal antibody called VRCO1. Read MoreApr 14, 2016
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Switching breast cancer off
Signaling by a receptor that is overexpressed in aggressive forms of breast cancer has been linked to glutamine metabolism, suggesting new anti-cancer therapeutic targets. Read MoreApr 14, 2016
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Report highlights global need for surgical services
An estimated 5 billion people — two-thirds of the world’s population — do not have access to surgery because of a lack of facilities, money and trained surgeons and anesthesiologists. Read MoreApr 8, 2016
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Potent HIV antibodies suggest new vaccine development approach
It’s been known for some time that the immune system can produce antibodies capable of “neutralizing” HIV, and stopping the AIDS-causing virus dead in its tracks. Read MoreApr 7, 2016
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Diabetes management and low income
Adherence to medication was the only self-care activity independently associated with glycemic control in a low-income population. Read MoreApr 6, 2016
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Immune defenses in asthma
Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease. Read MoreApr 5, 2016
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VUMC and Celgene Corporation enter into research agreement to accelerate development of next-generation therapeutics
Vanderbilt University Medical Center has entered into a strategic research agreement with Celgene Corporation, a biopharmaceutical company based in Summit, New Jersey. Read MoreApr 4, 2016
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Ariel Helms: Searching for a diabetes discovery
For Vanderbilt senior Ariel Helms from Oklahoma, twists and turns in her past, including a long-kept family secret, led to her passion for discovery in a Vanderbilt lab. Read MoreApr 1, 2016
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New role identified for p73 gene
The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility. Read MoreApr 1, 2016
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Study looks at doctors’ response to genetic testing
A new clinical implementation study from Vanderbilt University Medical Center measures how physicians have responded to the introduction of routine genetic testing to predict patient response to the commonly prescribed antiplatelet drug clopidogrel. Read MoreMar 31, 2016
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Cancer prevention and poverty
A new epidemiological study supports smoking cessation and avoidance of sedentary lifestyle as cancer prevention measures. Read MoreMar 31, 2016
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Readmission prediction face-off
Using patients’ health records to assess preparedness for hospital discharge is more effective at predicting readmission or death than commonly used questionnaires. Read MoreMar 23, 2016
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New treatment for Crohn’s disease
A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease. Read MoreMar 22, 2016
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Putting schizophrenia to bed
A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation. Read MoreMar 21, 2016
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ROCKs and cancer invasion
The rigidity of the microenvironment around cancer cells drives invasive behavior through distinct ROCK signaling pathways, which could guide the development of specific anti-invasive therapies. Read MoreMar 17, 2016
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Study suggests cancer’s ‘clock’ can be rewound
Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented. Read MoreMar 17, 2016
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Study explores gene’s role in protecting HIV patients from TB
An international research team led by scientists from Vanderbilt University Medical Center has identified a genetic variant that protects people with HIV from developing active tuberculosis. The variant is near the gene encoding the infection-fighting cytokine IL-12. Read MoreMar 17, 2016