Health And Medicine
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The discovery of a ‘negative regulator’ in the brain alters understanding of brain function and potential treatment of cognitive disorders
Terunaga Nakagawa and the Vanderbilt Brain Institute discover new qualities of GSG1L, responsible for activity in the anterior thalamus. Read MoreJul 21, 2020
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Study points to potential new approach to treating neurodegenerative diseases like glaucoma and Alzheimer’s disease
Researchers at Vanderbilt University Medical Center have shown for the first time that when one optic nerve in the eye is damaged, as in glaucoma, the opposite optic nerve comes to the rescue by sharing its metabolic energy. Read MoreJul 20, 2020
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Antibody research at Vanderbilt University Medical Center shows promise in fight against COVID-19
Based on positive results in preclinical studies reported today, potently neutralizing antibodies identified by researchers at Vanderbilt University Medical Center are showing promise as a potential therapy for preventing and treating COVID-19. Read MoreJul 15, 2020
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VUMC studies provide key positive results for COVID-19 vaccine in early-stage clinical trial
An experimental coronavirus vaccine stimulated robust immune responses against SARS-CoV-2, the virus that causes COVID-19, and raised no serious safety concerns in an early-stage clinical trial. Read MoreJul 14, 2020
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New tools to study bioactive lipids
Vanderbilt researchers have identified and characterized inhibitors of an enzyme that synthesizes lipid signaling molecules with roles in energy balance, inflammation and addiction. Read MoreJul 14, 2020
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“Nur” target may aid arthritis treatment
Vanderbilt immunologists have discovered that the protein Nur77 is part of a control mechanism that guards against autoimmunity in natural killer T cells. Read MoreJul 13, 2020
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New study supports remdesivir as COVID-19 treatment
This week researchers at Vanderbilt University Medical Center (VUMC), the University of North Carolina at Chapel Hill and Gilead Sciences reported that remdesivir potently inhibited SARS-CoV-2, the virus which causes COVID-19, in human lung cell cultures and that it improved lung function in mice infected with the virus. Read MoreJul 9, 2020
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Recurrent UTIs linked to hidden reservoir
Bacterial invasion of vaginal cells sets up a protective niche and a reservoir for recurrent urinary tract infections, Vanderbilt researchers demonstrated. Read MoreJul 9, 2020
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New space bolsters infectious disease and immunology discovery
The Vanderbilt Institute for Infection, Immunology and Inflammation (VI4) recently moved into its new research and administrative home. Read MoreJul 9, 2020
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Keeping beta cells “fit”
Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression. Read MoreJul 9, 2020
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Kripalani to lead Center for Health Services Research
Sunil Kripalani, MD, MSc, professor of Medicine at Vanderbilt University Medical Center, has been appointed director of the Vanderbilt Center for Health Services Research. Read MoreJul 9, 2020
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New clues to lung-scarring disease may aid treatment
Scientists at Vanderbilt University Medical Center and the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, have discovered previously unreported genetic and cellular changes that occur in the lungs of people with pulmonary fibrosis (PF). Read MoreJul 8, 2020
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Nurse researchers study expanded autonomy for advanced practice nurses during pandemic
Nurse leaders from Vanderbilt and two other prominent nursing schools in Tennessee are conducting a national study to measure the impact of a decision by state leaders to waive physician oversight of advanced practice registered nurses during the COVID-19 pandemic. Read MoreJul 8, 2020
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Research team isolates antibodies that may prevent rare polio-like illness in children linked to a respiratory infection
Researchers at Vanderbilt University Medical Center, Purdue University and the University of Wisconsin-Madison have isolated human monoclonal antibodies that potentially can prevent a rare but devastating polio-like illness in children linked to a respiratory viral infection. Read MoreJul 3, 2020
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VUMC-led network to focus on polygenic risk for common diseases
With the aid of a $75 million, five-year grant renewal, the Electronic Medical Records and Genomics Network (eMERGE) will venture beyond its current focus on monogenic disease to scoring research participants relative risk for complex heritable diseases such as cardiovascular disease, chronic kidney disease and type 2 diabetes. Read MoreJul 1, 2020
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VICTR named to key role to streamline COVID-19 research response
The Vanderbilt Institute for Clinical and Translational Research (VICTR), which provides comprehensive support for clinical and translational research at Vanderbilt University Medical Center (VUMC), has been named Administrative Coordinating Center (ACC) of a national effort to streamline the research response to life-threatening lung and heart problems caused by COVID-19. Read MoreJun 24, 2020
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Study shows better option for treatment of inoperable anal cancer
People with inoperable anal cancer treated with carboplatin-paclitaxel had fewer complications and lived longer than those who received another chemotherapy that has been more often administered. Read MoreJun 24, 2020
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Discovery of aggressive cancer cell types by Vanderbilt researchers made possible with machine learning techniques
Rebecca Ihrie and Jonathan Irish are leading the development of machine learning applications for brain cancer research. Read MoreJun 24, 2020
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Study finds zinc doesn’t reduce mortality, other health risks, for heavy alcohol users living with HIV/AIDS
Zinc supplementation did not reduce mortality, cardiovascular risk, levels of inflammation or microbial translocation among people with heavy alcohol use living with HIV/AIDS, according to a Vanderbilt-led study. Read MoreJun 24, 2020
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Glaucoma drug studied to prevent lung Infection in COVID-19 patients
Vanderbilt University Medical Center is evaluating razuprotafib, a drug used to treat glaucoma, in a new randomized, investigational trial for the prevention and treatment of acute respiratory distress syndrome (ARDS) in adult patients with moderate to severe COVID-19. Read MoreJun 24, 2020