Health And Medicine
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Slow traffic, fast food: The effects of highway congestion on fast-food consumption
According to new research from Panka Bencsik, assistant professor of medicine, health and society, on days when highways are more congested, particularly during weekday afternoon rush hour, people are more likely to choose the fast-food option. Read MoreFeb 20, 2025
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Developmental biologists discover how a critical protein shapes gallbladder formation
Researchers at Dr. Mark Magnuson's lab discovered that the formation of the gallbladder and bile duct system critically depends on the precise concentration of the Sox17 transcription factor, with even small reductions preventing gallbladder development in mice. Read MoreFeb 13, 2025
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Turning challenges into breakthroughs: Vanderbilt team develops self-sealing for dialysis membranes using proteins
Vanderbilt scientists developed new dialysis membranes using ultra-thin graphene that automatically seal larger holes while keeping smaller ones open, making them more effective than current medical filters and potentially improving dialysis treatment. Read MoreFeb 13, 2025
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Ultrasound imaging of breast cancer tumors offers non-invasive monitoring of radiation and immunotherapy response effectiveness
In the ongoing battle against triple negative breast cancer, Vanderbilt researchers have uncovered a promising non-invasive method to track how tumors respond to radiation and immunotherapy, which uses the body’s own immune system to fight cancer. Read MoreFeb 13, 2025
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Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
Recent research from the Warren Center for Neuroscience Drug Discovery, published in the Journal of Medicinal Chemistry, resulted in the proposal of a novel target and mechanism for improving cognition—a negative symptom—while also treating positive symptoms of the disease. Read MoreFeb 13, 2025
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Collector instincts and abstract thinking are behind immunologist James Crowe’s drive to use game-changing technology to prevent infectious disease
See how art collector turned immunologist James Crowe combines abstract thinking with game-changing technology to prevent infectious disease. Read MoreFeb 12, 2025
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Wellcome Trust Discovery award advances international collaboration to combat opioid misuse and addiction
Vanderbilt’s Carrie K. Jones and the University of Glasgow’s Andrew Tobin have received a prestigious £5 million ($6.2 million) Wellcome Trust Discovery Award to study how blocking the M5 muscarinic receptor in the brain could reduce opioid addiction while preserving pain relief. This groundbreaking international collaboration, supported by the Warren Center for Neuroscience Drug Discovery, aims to advance new treatments in the critical global health crisis of opioid use disorder. Read MoreFeb 10, 2025
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Vanderbilt researchers at forefront of global collaboration that advances preclinical imaging with diffusion MRI
Three seminal articles published in Magnetic Resonance in Medicine mark a landmark achievement in preclinical imaging science. These works, authored by an international consortium of 58 scientists, including Vanderbilt University’s Kurt Schilling, Bennett Landman, Adam Anderson, and Kevin Harkins, offer comprehensive guidelines for using diffusion magnetic resonance imaging (dMRI) in preclinical research. Read MoreFeb 6, 2025
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Pre-proposals now being accepted for 2025 NIH S10 Shared and High-End Instrumentation Grants
Submissions are open for pre-proposals for the 2025 National Institutes of Health S10 Shared and High-End Instrumentation Grant programs, which fund state-of-the-art shared research equipment. Internal pre-proposals are due by April 1, 2025, to allow institutional review before the June 2 NIH deadline, with guidance available from OVPRI and VBS. Read MoreJan 30, 2025
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Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
We often think about diseases in terms of the symptoms they present. A cold might give you the sniffles or even GI distress, while malaria can give you fever, chills, or nausea... Read MoreJan 30, 2025
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New center at Vanderbilt applies advanced technology to biological research
Vanderbilt University’s new Center for Computational Systems Biology brings computer science, engineering and biomedical researchers together with clinicians at Vanderbilt University Medical Center to accelerate discovery related to human diseases and conditions. Read MoreJan 16, 2025
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First successful clinical trial of VU319 brings Alzheimer’s treatment one step closer
Researchers at the Warren Center for Neuroscience Drug Discovery have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read MoreJan 9, 2025
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Doug Mitchell named professor of biochemistry and chemistry and director of the Vanderbilt Institute of Chemical Biology
Doug Mitchell has been appointed the holder of the William Kelly Warren Sr. Chair in Biochemistry and professor of chemistry and director of the Vanderbilt Institute for Chemical Biology. Read MoreJan 9, 2025
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First successful clinical trial of VU319 brings Alzheimer’s treatment one step closer
Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read MoreJan 9, 2025
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Eleven Vanderbilt scientists among world’s ‘highly cited’ researchers
Eleven current Vanderbilt University faculty members, 10 of whom are investigators at Vanderbilt University Medical Center, are included in the 2024 list of “Highly Cited Researchers” around the world whose papers have been cited most frequently by other scientists. Read MoreDec 19, 2024
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First successful clinical trial of VU319 brings Alzheimer’s treatment one step closer
Researchers at the Warren Center for Neuroscience Drug Discovery, a clinical stage biotech within the Vanderbilt University School of Medicine Basic Sciences, have detailed the successful drug discovery of a Phase I Single Ascending Dose clinical trial of VU319, a drug for memory loss in people with Alzheimer’s disease and schizophrenia. Read MoreDec 19, 2024
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Vanderbilt researchers find evidence that the hunger hormone leptin can direct neural development in a leptin receptor–independent manner
Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry. Read MoreDec 5, 2024
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Research Snapshot: Spectroscopy and AI method provide unique window into protein structure and mechanism of action
The lab of Hassane Mchaourab, director of the Center for Applied Artificial Intelligence in Protein Dynamics and professor of molecular physiology and biophysics, has developed a methodological blueprint that couples experimental double electron–electron resonance spectroscopy with an AI approach to help describe the conformational landscapes of a diverse spectrum of cell membrane transporters. Read MoreDec 4, 2024
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Vanderbilt awarded up to $46M through ARPA-H to develop tools against alphaviruses
Jens Meiler, Distinguished Research Professor of Chemistry, was named the principal investigator for the project, in cooperation with 14 investigators across eight institutions. The team will work together to use advanced technology, including computational modeling, AI-driven predictions and structural biology, to develop a groundbreaking vaccine against all alphaviruses that offers long-lasting protection. Read MoreDec 2, 2024
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Analyzing police shootings, public safety, and policy
A series of three recently published studies have provided the first nationally comprehensive analysis of shootings by law enforcement officers that injured or killed people in the U.S. Led by Julie Ward, assistant professor of medicine, health, and so... Read MoreNov 22, 2024