Leigh MacMillan

Blocking a serotonin receptor may provide a novel therapy for heart valve disease. Read More

Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer. Read More

A new study identifies interactions between genes and nutrients that may participate in determining levels of cholesterol and triglycerides. Read More

Noted neuroscientist Thomas Südhof, M.D., will deliver the next Flexner Discovery Lecture on Thursday, Dec. 13. Read More

A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging. Read More

The recent “Diabetes Day” symposium recognized two Vanderbilt trainees for their potential as future leaders in diabetes research and one longtime staff member for his service to the diabetes research community. Read More

There’s been an explosion in the world of RNA — the nucleic acid “copy” of DNA, Nobel laureate Phillip Sharp, Ph.D., told the crowd gathered for his Flexner Discovery Lecture. Read More

Lynne Maquat, Ph.D., the J. Lowell Orbison Endowed Chair and professor of Biochemistry & Biophysics at the University of Rochester, will deliver the next Flexner Discovery Lecture on Thursday, Dec. 6. Read More

The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model. Read More

The main antioxidant compound in green tea increases contractile force in isolated heart cells, suggesting it may be useful in heart failure. Read More

Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention. Read More

An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations. Read More

Nobel laureate Phillip Sharp, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, Nov. 15. Read More

“Diabetes at Vanderbilt: From Molecules to People,” a scientific symposium to highlight diabetes research at Vanderbilt, will take place Wednesday, Nov. 14, from 10 a.m. to 2:30 p.m. in the Vanderbilt Student Life Center. Read More

Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure. Read More

The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells. Read More

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer. Read More

New findings from Vanderbilt researchers may explain why only some individuals who have inherited mutations that increase risk for pulmonary hypertension actually develop the disease. Read More

A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function. Read More

An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease. Read More