Leigh MacMillan

Nobel laureate Michael Brown, M.D., whose research paved the way for the development of cholesterol-lowering statin drugs, will deliver the next Flexner Discovery Lecture on Thursday, April 25. Read More

After 40 years in basic science working with yeast cells, Nobel laureate Lee Hartwell, Ph.D., has turned his attention in a new direction. Read More

A gene associated with cell survival and longevity may protect the kidney from acute injury. Read More

Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy. Read More

Targeting repair pathways in the lung’s air sacs may be a valuable therapeutic direction for pulmonary fibrosis – the scarring of lung tissue. Read More

Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous. Read More

Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11. Read More

Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes. Read More

The gene Has2 participates in signaling that is important in developing fingers and toes, and may have relevance for cancer development. Read More

Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy. Read More

Sir Rory Collins, MB BS, professor of Medicine and Epidemiology at the University of Oxford, England, will deliver the next Flexner Discovery Lecture on Thursday, April 4. Read More

In critically ill patients with sepsis, plasma hemoglobin may be a new indicator of disease severity – and a potential target for treatment with acetaminophen. Read More

A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors. Read More

The factor IRF6 plays important roles in the development of the tongue. Read More

Diagnostic codes used for billing purposes effectively identify smokers in a general clinic population and can be used to adjust smoking status in genetic and epidemiologic studies. Read More

Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs. Read More

An international group of investigators has identified seven new genetic regions associated with age-related macular degeneration (AMD), a common cause of blindness in older individuals. Read More

An ultrasound count of potentially egg-producing follicles could predict the timing of menopause. Read More

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments. Read More

Charles Sanders, Ph.D., professor of Biochemistry, has been selected as a recipient of the 2013 Hans Neurath Award from the Protein Society. He shares the honor with Jennifer Doudna, Ph.D., a Howard Hughes Medical Institute investigator at the University of California, Berkeley. Read More