Bill Snyder
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Antibodies eye Pacific Island “fever”
Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read MoreMay 14, 2020
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New method captures early viral-host protein interactions
Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins. Read MoreMay 7, 2020
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Antibody finding raises hopes for Marburg, COVID-19 treatments
Monoclonal antibodies against Marburg virus — a more lethal cousin of the RNA virus that causes COVID-19 — may aid in the development of antibody "cocktails" to counter viral infection. Read MoreApr 30, 2020
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Blocking stress-induced relapse
Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders. Read MoreApr 8, 2020
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VUMC team aids development of potential antiviral drug for COVID-19
Researchers at Vanderbilt University Medical Center are playing a key role in the development of a potential new antiviral drug to treat COVID-19. Read MoreApr 6, 2020
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Triple-negative breast cancer drug therapy shows promise
Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. Read MoreMar 12, 2020
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Breast cancer study may help predict treatment response
Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat. Read MoreFeb 27, 2020
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Potential new heartburn drug studied at VUMC
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests. Read MoreFeb 26, 2020
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Protein interactions and brain function
Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read MoreFeb 20, 2020
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Post-transplant diabetes may be reversible: study
Post-transplantation diabetes mellitus (PTDM), a common complication of immunosuppressive drugs that are given to prevent transplant rejection, may be reversible and at least partially preventable, researchers at VUMC report. Read MoreFeb 20, 2020
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Vanderbilt University Medical Center among top 100 proposals for MacArthur Foundation $100 million grant
The John D. and Catherine T. MacArthur Foundation today unveiled a grant proposal from Vanderbilt University Medical Center (VUMC) as one of the highest-scoring proposals, designated as the “Top 100,” in its 100&Change competition for a single $100 million grant to help solve one of the world’s most critical societal challenges. Read MoreFeb 19, 2020
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Algorithm helps improve coronary calcium detection
A new algorithm for artificial intelligence-assisted calcium scoring can accurately determine cardiovascular risk across a range of CT scans and in a racially diverse population. Read MoreFeb 13, 2020
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Antibody mixture may help block Ebola virus infection
A research team led by scientists at Vanderbilt University Medical Center has developed an antibody mixture that in animals is highly effective in blocking infection by the Ebola virus. Read MoreFeb 6, 2020
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Conn, Calipari to receive major pharmacology awards
Two Vanderbilt University pharmacologists have won prestigious awards from the American Society for Pharmacology and Experimental Therapeutics (ASPET). Read MoreFeb 6, 2020
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Team tracks integrin’s role in lung function
Beta-1 integrin, a critical component of epithelial extracellular matrix receptors, is essential for normal lung function in adulthood, researchers at VUMC have discovered. Read MoreFeb 6, 2020
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Protein research seeks to induce tumor regression
MYC is a family of three related proteins that are overexpressed in cancer and which contribute to an estimated 100,000 cancer deaths annually in the United States. Understanding how MYC works could lead to the development of new drugs that can effectively block MYC and stop many cancers in their tracks. Read MoreJan 29, 2020
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Kavalali receives Humboldt Research Award
Ege T. Kavalali, PhD, professor and acting chair of the Department of Pharmacology in the Vanderbilt University School of Medicine, has been elected a recipient of a prestigious Humboldt Research Award by the Alexander von Humboldt Foundation of Germany. Read MoreDec 31, 2019
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VUMC-led team isolates antibody that blocks bird flu
VUMC scientists are redoubling their efforts to help people fight off bird flu. Their focus is H7N9, one of the most dangerous of the influenza viruses that have been transmitted from birds to humans. Read MoreDec 12, 2019
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Study examines HIV drug’s potential to treat Alzheimer’s
A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease. Read MoreDec 12, 2019
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Study reveals mysteries of critical brain receptor complex
Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions. Read MoreDec 5, 2019