Skip to main content

Author: Bill Snyder

Study reveals mysteries of critical brain receptor complex

Dec. 5, 2019—Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

Read more


Study finds ‘frozen’ fear response may underlie PTSD

Nov. 27, 2019—To explore how fear becomes entrenched, VUMC researchers traveled down the precise neuronal pathways in the brains of mice that trigger fear responses, and which normally extinguish the behaviors once the danger has passed.

Read more


Study explores potential new class of antidepressants

Nov. 21, 2019—Researchers at VUMC have taken a major step that could ultimately facilitate development of a new class of antidepressants which may relieve symptoms more rapidly and effectively and with fewer side effects than current medications.

Read more


Blueprint for treating epilepsy

Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.

Read more


Endotoxin shock protector

Nov. 5, 2019—A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.

Read more


Less inflammation = better healing

Oct. 17, 2019—Immune cells that produce an anti-inflammatory factor are enriched in fat tissue around the heart and may be good targets to improve heart attack outcomes.

Read more


Nobel laureate Südhof reviews his landmark signaling research

Oct. 10, 2019—The human brain consists of perhaps as many as 1,000 trillion synapses, which transmit signals from one nerve cell to another with amazing speed, precision and plasticity.

Read more


Team discovers one more piece to the autism puzzle

Oct. 3, 2019—Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability.

Read more


Study shines light on architecture of kidney disease

Sep. 25, 2019—A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.

Read more


Guengerich, Sanders-Bush named ASPET fellows

Sep. 20, 2019—Vanderbilt University’s F. Peter (Fred) Guengerich, PhD, and Elaine Sanders-Bush, PhD, are among 22 prominent scientists named this week to the inaugural class of fellows of the American Society for Pharmacology and Experimental Therapeutics (ASPET).

Read more


The plus and minus of microtubules

Sep. 5, 2019—Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.

Read more


Zebrafish aid effort to regenerate damaged retinas

Sep. 5, 2019—According to a new study, the tiny zebrafish may hold the secret to regenerating damaged retinas in humans.

Read more


VIEW MORE EVENTS >