Year: 2020
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Study explores the role of MYCN in Triple Negative Breast Cancer diagnosis and treatment
The oncogene MYCN regulates cancer cell growth, proliferation, metabolism, and survival; tumors with increased MYCN expression are more aggressive. Read MoreSep 10, 2020
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Award supports integration of genomic data, electronic health records
Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records. Read MoreSep 10, 2020
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VUMC to lay groundwork for Tennessee’s first federally funded Alzheimer’s Disease Research Center
Angela Jefferson, PhD, professor of Neurology and director of the Vanderbilt Memory and Alzheimer’s Center, has been awarded a $3.7 million, three-year grant from the National Institute on Aging (NIA) to support establishment of a prospective NIA-funded Alzheimer’s Disease Research Center (ADRC) at Vanderbilt University Medical Center. Read MoreSep 10, 2020
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Fibroids and birth outcomes
Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read MoreSep 8, 2020
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Possible key to COVID-19 infectivity
New findings demonstrate how genetic variations in the receptor that binds SARS-CoV-2 impact virus recognition and infectivity and offer insights to COVID-19 susceptibility and treatment. Read MoreSep 7, 2020
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Ethnic fears eroding democratic attitudes among Republicans, new research finds
Ethnocentric concerns about the growing political power and social influence of immigrants, African Americans and Latinos are undermining Republicans’ commitment to long-held democratic norms, according to new research by Vanderbilt University political science professor Larry Bartels. Read MoreSep 4, 2020
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New clue to Alzheimer’s disease
Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease. Read MoreSep 3, 2020
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Assembling cell power plant machinery
Tina Iverson and colleagues provide a structural view into the assembly of a protein machine essential for cellular energy production. Read MoreSep 3, 2020
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Incarceration of family members negatively impacts mental health outcomes for African American women
A new study sheds new light on the challenges facing African American women. More than half of all African American women in the United States report having at least one family member who is incarcerated, causing higher levels of depressive symptoms and psychological distress than previously understood. Read MoreSep 2, 2020
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Finding the right emotional ‘match’ makes for better business relationships
When it comes to creating successful business interactions, exchanges between buyers and sellers with similar emotional abilities may lead to more lucrative outcomes than an animated or ambitious employee alone. Read MoreSep 2, 2020
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Grissom awarded $1.4 million NIH grant to develop smaller, quieter MRI system
Vanderbilt engineers have received a $1.4 million NIH grant to work toward a compact, silent, less expensive and potentially portable MRI device. Read MoreSep 1, 2020
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Vanderbilt students give university high marks for financial aid, counseling services
Vanderbilt ranked No. 1 in the “Great Financial Aid” and “Their Students Love These Colleges” categories in The Princeton Review’s latest Best Colleges rankings. The university also ranked No. 3 for “Best Counseling Services” based on students’ positive opinion of the support and counseling services they receive at Vanderbilt. Read MoreAug 31, 2020
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Vip1 allows cells to adapt to changing conditions
Research shows how the actions of Vip1 help cells change their shape in response to environmental conditions. Read MoreAug 28, 2020
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Non-neutralizing antibodies from a Marburg infection survivor show therapeutic potential
By Sohini Roy Marburg viruses cause a hemorrhagic fever in humans, with a fatality rate of up to 90 percent. Currently, Marburg disease can neither be prevented by a vaccine nor therapeutically treated. Understanding how the immune system of a MARV survivor reacts against the virus can yield clues to design a treatment. With this... Read MoreAug 28, 2020
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Study to track if COVID can spread during minimally invasive surgery
Physician-scientists at Vanderbilt University Medical Center are investigating whether SARS-CoV-2, the virus that causes COVID-19, can be spread through aerosolized emissions (microscopic droplets and particles) during minimally invasive surgery in children. Read MoreAug 27, 2020
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Study uses AI to sort patient messages by complexity
Taking an interest in electronic message threads between surgical patients and their health care teams, a research group at Vanderbilt University Medical Center has tested how well certain commonly used machine learning algorithms can classify such exchanges according to their clinical decision-making complexity. Read MoreAug 27, 2020
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Blocking tumor ‘signals’ and ‘fuel’
Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients. Read MoreAug 25, 2020
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Land of plenty (of opioids)
Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction. Read MoreAug 24, 2020
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VUMC awarded $34 million to lead nationwide convalescent plasma study
Vanderbilt University Medical Center has been awarded a one-year, $34-million grant by the National Center for Advancing Translational Sciences, part of the National Institutes of Health, to conduct a nationwide study of “convalescent plasma” as a treatment for COVID-19. Read MoreAug 21, 2020
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Salt, immune cells and hypertension
Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption. Read MoreAug 20, 2020