Endocytosisis a highly regulated process in which cells take up substances packaged in vesicles by internalizing the plasma membrane surrounding the cargo.
In yeast, the enzyme Rsp5 regulates most endocytic events with the help of arrestin-related Rsp5 adaptor proteins called ARTs. Yet much remains to be learned about how this extraordinarily complex cellular machinery works.
Reporting this month in the Journal of Cell Biology, Jason MacGurn, PhD, and colleagues focus on the essential amino acid methionine.