Publisher: Social Cognitive and Affective Neuroscience
Authors: Emily L Dennis, Kathryn L Humphreys, Lucy S King, Paul M Thompson, Ian H Gotlib
Irritability is garnering increasing attention in psychiatric research as a transdiagnostic marker of both internalizing and externalizing disorders. These disorders often emerge during adolescence, highlighting the need to examine changes in the brain and in psychological functioning during this developmental period.
Publisher: Journal of Abnormal Child Psychology
Authors: Katherine L Guyon-Harris, Kathryn L Humphreys, Devi Miron, Mary Margaret Gleason, Charles A Nelson, Nathan A Fox, Charles H Zeanah
Psychosocial deprivation is associated with the development of socially aberrant behaviors, including signs of disinhibited social engagement disorder (DSED). In longitudinal studies, signs of DSED have been shown to decrease over time, especially as children are removed from conditions of deprivation.
Publisher: Development and Psychopathology
Authors: Katharina Kircanski, Lucinda M Sisk, Tiffany C Ho, Kathryn L Humphreys, Lucy S King, Natalie L Colich, Sarah J Ordaz, Ian H Gotlib
Early life stress (ELS) is a risk factor for the development of depression in adolescence; the mediating neurobiological mechanisms, however, are unknown. In this study, we examined in early pubertal youth the associations among ELS, cortisol stress responsivity, and white matter microstructure of the uncinate fasciculus and the fornix, two key frontolimbic tracts; we also tested whether and how these variables predicted depressive symptoms in later puberty.