Zhongming Zhao
-
Drug signaling networks
Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action. Read MoreJul 15, 2015
-
New data mining method reveals cancer-driving genes
Prospecting for genes that might be implicated in cancer, a Vanderbilt University Medical Center research team has struck pay dirt. Read MoreJan 22, 2015
-
Protein “pockets” help ID cancer genes
Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response. Read MoreNov 11, 2014
-
Bradfords’ strong support bolsters melanoma research
When something attacks you, you want to attack it back. That’s how Lillian “Tooty” Bradford views her late husband James “Jimmy” Bradford Jr.’s decision to make an initial gift to fund melanoma research at Vanderbilt-Ingram Cancer Center (VICC). Read MoreSep 25, 2014
-
VU study reveals shared pathways in psychiatric disorders
Schizophrenia and bipolar disorder share common genetic underpinnings. Vanderbilt researchers combined high-resolution gene expression studies with gene association data to reveal signaling pathways linked to schizophrenia and bipolar disorder. Read MoreSep 18, 2014
-
Drug discovery clues in network map
Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies. Read MoreAug 5, 2014
-
Web tool speeds pulmonary hypertension discovery
The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis. Read MoreMar 5, 2014
-
Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
-
Gene interactions and cavities
Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay. Read MoreSep 30, 2013
-
VU study identifies DNA changes in drug-resistant cancer cells
Vanderbilt investigators have combined next-generation sequencing technologies and bioinformatics analyses to screen for genome-wide genetic mutations associated with drug resistance in a series of lung cancer cell lines. Read MoreSep 12, 2013
-
Network approach yields glioblastoma clues
MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor. Read MoreAug 9, 2012
-
Study finds mutation in melanoma sensitive to drug
An uncommon mutation of the BRAF gene in melanoma patients has been found to respond to a specific drug therapy, providing a rationale for routine screening and therapy in melanoma patients who harbor the BRAF L597 mutation. Read MoreJul 26, 2012
-
Gene database to aid disease research
A new catalog of human genetic data may help researchers uncover the genetic roots of disease and enable the ultimate realization of personalized medicine. Read MoreJun 19, 2012
-
Tool finds connections in genome data
A new analytical tool points to genes that act together to increase disease risk. Read MoreFeb 8, 2012