Virus

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read More

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA. Read More

Vanderbilt Vaccine Center team isolates monoclonal antibodies against the mosquito-borne Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months. Read More

John Karijolich, PhD, assistant professor of Pathology, Microbiology, and Immunology at Vanderbilt University Medical Center, has been named a Pew Biomedical Scholar by The Pew Charitable Trusts. Read More

Genomic sequences have revealed that Florida is a major source of a mosquito-borne virus that causes disease in horses and humans. Read More

A new Vanderbilt study suggests it may be possible to develop antibody therapies or a universal vaccine effective against multiple Ebola virus family members. Read More

Targeting the protein that mosquito-borne viruses use to enter cells could be a strategy for preventing infection by multiple emerging viruses. Read More

A comfort, not a hazard. When you are home sick, snuggling up with your dog or cat may feel like just what the doctor ordered. And a Vanderbilt infectious disease doctor, while stopping short of actually prescribing in-home “pet therapy” for colds or… Read More

Compounds developed at Vanderbilt University may offer a new way to block influenza infection. Read More

Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments. Read More

Virus-like particles containing a protein from human metapneumovirus are a promising vaccine candidate for this respiratory virus. Read More

Understanding how chikungunya virus binds to and enters cells offers a new target for antiviral medications. Read More

Vanderbilt’s James Crowe Jr., M.D., and a collaborator in Texas have been awarded a $4.4 million grant from the U.S. Department of Defense to study new ways to treat and prevent Ebola and Marburg viruses. Read More

An immune system factor associated with severe asthma may actually reduce asthma attacks induced by viral infections. Read More

Components of human breast milk help ward off viral infection, a new study shows. Read More

The structural architecture of the reovirus attachment protein is required for efficient reovirus infection of host cells. Read More

The protein APOBEC3G contributes to spontaneous control of HIV-1 in vivo and may provide therapeutic benefits. Read More

The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells. Read More

Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells. Read More

A new viral protein structure could jump-start vaccine development for two leading causes of lower respiratory disease in children and elderly adults. Read More