VI4
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Vanderbilt’s Life Science Showcase focuses on cutting-edge infectious disease research
Infectious diseases pose a significant global health challenge, accounting for a substantial proportion of deaths worldwide, according to recent data from the World Health Organization. Vanderbilt’s Life Science Showcase: Advancing Innovation in Infectious Diseases held on July 18 emphasized the vital importance of advancing research and innovation to combat these persistent threats. Read MoreJul 23, 2024
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Gut microbiota metabolite protects against obesity: study
Vanderbilt researchers have discovered that beneficial bacteria in the small intestines produce a compound that protects against obesity. Read MoreDec 8, 2023
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Pasteurization reduces bioactive component of breast milk
Pasteurization of breast milk affects the concentration of osteopontin, a bioactive protein with roles in intestinal, immunological and brain development — suggesting that osteopontin supplementation should be considered when donor milk is provided to preterm infants. Read MoreDec 6, 2023
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Novel C. diff structures are required for infection, offer new therapeutic targets
Vanderbilt research discovers that iron storage “spheres” inside the bacterium C. diff — the leading cause of hospital-acquired infections — are important for infection in an animal model and could offer new targets for antibacterial drugs. Read MoreNov 15, 2023
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‘Molecular Muse’ showcases artwork from Vanderbilt Institute for Infection, Immunology and Inflammation Artist-in-Residence program at Fine Arts Gallery
Undergraduate artists, biomedical researchers join forces to convey the power and promise of Vanderbilt research labs through visual art on display at the Fine Arts Gallery and throughout biomedical research spaces on campus through Nov. 17. Read MoreAug 23, 2023
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Study details RNA editing in virus-infected cancer cells
Vanderbilt researchers detail the landscape of RNA editing — a form of RNA modification — in primary effusion lymphoma cells during Kaposi’s sarcoma-associated herpesvirus infection and identify an edited viral microRNA that is critical for infection. Read MoreApr 20, 2023
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Mathers Foundation award supports study of bacterial physiology
Vanderbilt's Wenhan Zhu, PhD, has received a three-year award from the G. Harold and Leila Y. Mathers Foundation to support his research that aims to answer a fundamental question about bacterial physiology and engineer probiotics to improve gut inflammatory diseases. Read MoreMar 23, 2023
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Study identifies key player in T cell “education”
New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output. Read MoreSep 1, 2022
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Vanderbilt researchers discover how gut inflammation leads to bone loss
Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss. Read MoreAug 25, 2022
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Study describes how E. coli co-opts cells, causes recurrent UTIs
Researchers at Vanderbilt University Medical Center have discovered why the uropathogenic bacterium E. coli, the leading cause of urinary tract infections, is so tenacious; their findings could lead to new ways to prevent recurrent UTIs. Read MoreAug 25, 2022
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Study identifies first cellular “chaperone” for zinc, sheds light on worldwide public health problem of zinc deficiency
A team led by Vanderbilt researchers has described and characterized the first zinc metallochaperone: a protein that puts zinc into other “client” proteins. Read MoreMay 17, 2022
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VUMC team discovers how bacterial pathogen survives without water
Vanderbilt researchers are studying a bacterial pathogen that can survive on hospital surfaces — without water — for months, an ability that has helped it become a leading cause of hospital-acquired infections. Read MoreMay 5, 2022
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Study advances understanding of bacterial bioterrorism agent
Vanderbilt researchers have identified a critical regulatory factor in the bacterium that causes the disease anthrax and has been used as a biological weapon. Read MoreApr 7, 2022
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Impaired neutrophils in autoimmunity
Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity. Read MoreJan 27, 2022
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H. pylori, lipid loss and stomach cancer
H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read MoreJan 17, 2022
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Salmonella overcomes host resistance
The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization. Read MoreJan 13, 2022
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Vanderbilt Microbiome Innovation Center launched as hub for resources, education, and research
The Vanderbilt Microbiome Initiative has been renamed the Vanderbilt Microbiome Innovation Center. It will offer a hub of resources for education, outreach and research around the microbiome—the community of microorganisms such as bacteria, fungi and viruses that are crucial to sustaining life ecosystems. Read MoreOct 27, 2021
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Research Snapshot: Sugar compounds in breast milk relieve uncomfortable side effects caused by chemotherapy
Steven Townsend, associate professor of chemistry, and Fang Yan, research professor of pediatrics and cell and development biology, have discovered how a sugar in human breast milk mitigates damage to the small intestines caused by chemotherapy-induced mucositis. Read MoreOct 4, 2021
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Applications for summer 2021 VI4 Artist in Residence Program now open to students nationwide
The summer 2021 Artist in Residence program applications are now open to all undergraduate students nationwide. Applications submitted online will be accepted until April 2. The residency is facilitated by the Vanderbilt Institute for Infection, Immunology and Inflammation. Read MoreMar 30, 2021
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Temperature, newts, and a skin-eating fungus
The emergence of pathogenic skin fungi that cause the disease chytridiomycosis is contributing to the global loss of amphibian populations. Read MoreMar 8, 2021