Vanderbilt Center for Structural Biology
Vanderbilt biochemists reveal the cause of Charcot-Marie-Tooth disease—too much of a good thing
Oct. 27, 2020—Vanderbilt researchers—including Charles Sanders, associate dean for research and professor of biochemistry, and graduate student Justin Marinko—have illuminated the cause of Charcot-Marie-Tooth disease, putting them on the road to developing therapeutic approaches for the disease that affects one in 2,500 people.
A key to calcium signaling
Feb. 11, 2020—Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.
Poster session Friday will feature work on next-gen vaccines
Aug. 6, 2018—The computer-aided design and engineering of antibodies and vaccine candidates that can neutralize viral scourges like influenza and Ebola will be the topic of an Aug. 17 poster session presented by the Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center.
New view of the heartbeat
Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.
Noted neuroscientist Gouaux set for Discovery Lecture
Feb. 15, 2018—Eric Gouaux, PhD, whose work has helped reveal the molecular mechanisms by which nerve cells communicate, will deliver the next Flexner Discovery Lecture Thursday, Feb. 22.
DNA damage repair: molecular insights
Dec. 5, 2017—Structural details about a protein involved in the repair of damaged DNA provide insight into xeroderma pigmentosum disorders, which are characterized by increased risk for skin cancer.
Repriming replication roadblocks
Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.
A new mode of DNA repair
Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.
Symposium on Modeling Immunity set for April 27
Apr. 5, 2017—The Vanderbilt Center for Structural Biology and the Vanderbilt Vaccine Center invite you to attend the 2017 Symposium on Modeling Immunity April 27. The event will focus on modeling and designing antibodies.
Symposium on modeling immunity set for April 27
Mar. 30, 2017—The 2017 Vanderbilt Symposium on Modeling Immunity will be held from 1 to 4:30 p.m. Thursday, April 27, in room 1220 MRB III.
Team identifies ‘switch’ involved in DNA replication
Feb. 23, 2017—DNA replication is an extraordinarily complex multi-step process that makes copies of the body’s genetic blueprint. It is necessary for growth and essential to life. Now researchers at the California Institute of Technology (Caltech) and Vanderbilt University have found evidence that one of those steps may involve the telephone-like transmission of electrical signals regulated by a chemical “switch.”
Transcription factor evolution
Aug. 11, 2016—Vanderbilt researchers have discovered a novel model of evolution for factors that control gene expression.