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Vanderbilt Center for Bone Biology Archives

Stress may switch on bone “mets”

Aug. 9, 2017—New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes.

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Unal receives Orthopedic Research Society award

Jun. 15, 2017—Mustafa Unal, Ph.D., a postdoctoral research fellow at Vanderbilt University School of Medicine, has been selected by the Orthopedic Research Society to receive its 2017 Alice L. Jee Young Investigator Award for work that potentially will improve the clinical assessment of bone strength and quality.

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Diabetes study seeks to identify biomarkers for fracture risk

Oct. 20, 2016—Medical studies have established that people with type 2 diabetes are more susceptible to fractures, but the biological process that weakens their bones is not understood.

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Wound-healing scaffolds

Jan. 27, 2016—The elasticity of a scaffold used for healing skin wounds is a key factor in promoting regeneration versus scarring.

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VUMC study shifts thinking on how bone fractures heal

Aug. 13, 2015—New findings show that fibrin, a protein that was thought to play a key role in fracture healing, is not required, shifting understanding of how fractures heal.

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Targeting bone metastasis

Jul. 23, 2015—The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.

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Neurofibromin fine-tunes bone growth

May. 6, 2015—The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

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Inner ear keeps bones strong

Jan. 14, 2015—Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel.

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Physician-scientist is dream job for Vanderbilt’s Cassat

Dec. 4, 2014—Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.

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Bone healing therapy for NF1 fractures

Sep. 11, 2014—A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.

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Aggressive bone cancers build more blood vessels

Sep. 3, 2014—A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

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Novel treatment strengthens bones in genetic disease

Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

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