Tumor Suppressor

A new study by Vanderbilt researchers provides a remarkably detailed view of the earliest events leading to the development of cancer, and of potential new ways to prevent it. Read More

Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo. Read More

More than a decade after the anti-inflammatory drugs Vioxx and Bextra were pulled from the market because of a heightened risk of heart attack and stroke in some patients, COX-2 inhibitors may be on the verge of a comeback, this time as anti-cancer agents. Read More

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer. Read More

A protein involved in repairing DNA damage associated with gastric reflux may play a tumor suppressor role in the esophagus and could represent a target for therapies to combat esophageal cancer. Read More