Stomach Cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read More

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read More

Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read More

New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read More

The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read More

Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read More

Vanderbilt University Medical Center cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions. Read More

Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read More

Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment. Read More

Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk. Read More

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read More

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read More

A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read More

Jordan Berlin, M.D., professor of Medicine and Ingram Professor of Cancer Research at Vanderbilt-Ingram Cancer Center, has received the Tree of Life award from Debbie’s Dream Foundation: Curing Stomach Cancer (DDF). Read More

A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population. Read More

Archived tissue samples are yielding new disease biomarkers. Read More

Green tea may lower risk of some digestive cancers. Read More