Stomach Cancer
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Fatty acids rewire energy supply chain in stomach cancer development
A study by Vanderbilt researchers has revealed how metabolic changes spurred by fatty acids contribute to the transformation of cells into abnormal versions of themselves that are the precursors to stomach cancer. Read MoreJan 31, 2024
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H. pylori, lipid loss and stomach cancer
H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered. Read MoreJan 17, 2022
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Stomach bug hit-and-run
The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate. Read MoreJul 23, 2020
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Powering H. pylori pathogenesis
Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer. Read MoreFeb 6, 2020
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A step toward gastric cancer
New research findings provide insight into the detrimental events that develop in response to H. pylori infection. Read MoreOct 3, 2019
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Toxin floats on lipid rafts
The bacterium H. pylori is a leading cause of stomach cancer, and Vanderbilt researchers are studying how one of its toxins gets into cells. Read MoreApr 23, 2018
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Early drivers of gastric cancer
Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers. Read MoreAug 8, 2017
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Study seeks to reverse precancerous stomach lesions
Vanderbilt University Medical Center cancer researcher James Goldenring, M.D., Ph.D., has received a two-year, $200,000 grant from the DeGregorio Family Foundation in Pleasantville, New York, to begin clinical trials of a potential approach for reversing precancerous stomach lesions. Read MoreMay 4, 2017
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A DARPP role in gastric cancer
Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies. Read MoreNov 3, 2016
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VUCast Extra: Making a Difference in Latin America
From a new product to combat childhood malnutrition in Guatemala to a low-cost capsule for stomach cancer screenings to preserving the history of slave societies, Vanderbilt is helping find solutions, making discoveries and changing lives. Read MoreNov 12, 2015
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Stomach cancer cues
Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment. Read MoreAug 6, 2015
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Host sequesters zinc to control stomach bug
Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk. Read MoreNov 21, 2014
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Therapeutic target for gastric cancer
A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies. Read MoreDec 12, 2013
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Cell changes en route to stomach cancer
Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer. Read MoreSep 26, 2013
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Noninvasive test detects stomach bug
A noninvasive test can be used to identify the presence of Helicobacter pylori and evaluate its virulence, which will be useful in areas with high rates of H. pylori-associated gastric cancer. Read MoreAug 12, 2013
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Berlin earns stomach cancer foundation award
Jordan Berlin, M.D., professor of Medicine and Ingram Professor of Cancer Research at Vanderbilt-Ingram Cancer Center, has received the Tree of Life award from Debbie’s Dream Foundation: Curing Stomach Cancer (DDF). Read MoreMay 30, 2013
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Salt revs stomach bug’s cancer impact
A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population. Read MoreMay 13, 2013
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Cancer markers from archived tissue
Archived tissue samples are yielding new disease biomarkers. Read MoreDec 20, 2012
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Green tea found to reduce rate of some GI cancers
Green tea may lower risk of some digestive cancers. Read MoreOct 31, 2012