Stem Cells
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Michael R. King named National Academy of Inventors Fellow
Vanderbilt University engineering professor Michael R. King has been elected a fellow of the National Academy of Inventors, the highest professional distinction accorded solely to academic inventors. Read MoreDec 8, 2022
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Motor protein linked to intestinal cell differentiation
The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered. Read MoreAug 5, 2021
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Structure of a stem cell niche
Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies. Read MoreFeb 28, 2018
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Stem cells promote tolerance
Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered. Read MoreNov 17, 2016
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Proliferative capacity of neuroblastoma
The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma. Read MoreAug 31, 2016
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Hhex on cancer
A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production. Read MoreJul 13, 2015
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Delivering cells for heart repair
A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair. Read MoreJul 10, 2015
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Boosting cell-based heart repair
A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells. Read MoreMay 15, 2015
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Long-range signaling to stem cells
The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis. Read MoreOct 9, 2014
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Patient-derived stem cells shed light on pulmonary hypertension
Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies. Read MoreSep 16, 2014
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Engelhardt lands stem cell transplant research grant
Up to 60 percent of patients who receive a stem cell transplant using cells from another donor will develop post-transplant diabetes mellitus, which can increase the rate of complications and death after the procedure. Read MoreSep 11, 2014
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Study finds coronary arteries hold heart-regenerating cells
Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered. Read MoreAug 20, 2014
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Leukemia culprit’s cellular actions
Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous. Read MoreApr 11, 2013
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Bid protein guards blood cells against stress
A protein normally known to promote cell death found to encourage survival of blood forming cells. Read MoreOct 25, 2012
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Long live the therapeutic stem cells
Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help. Read MoreMay 17, 2012
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Stem cells take heart
Signaling pathway discoveries suggest ways to induce stem cells to become cardiac muscle cells, which could be useful for regenerating damaged heart muscle. Read MoreFeb 20, 2012
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Pumping up the pancreas in pregnancy
A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications. Read MoreJan 20, 2012