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Staphylococcus aureus Archives

Excess dietary manganese increases risk of staph infection in heart

Sep. 21, 2017—Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus (“staph”).

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Investigators use light to kill microbial ‘vampires’

Jul. 27, 2017—On July 24 Vanderbilt scientist Eric Skaar, Ph.D., MPH, summarized his group’s latest paper in a tweet: “If S. aureus is going to drink our blood like a vampire, let's kill it with sunlight.”

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New approach for staph-related skin abscesses explored

Jul. 13, 2017—New multicenter research that includes Vanderbilt University Medical Center (VUMC) investigators, could change treatment approaches to simple skin abscesses, infections often caused by Staphylococcus aureus (staph) bacteria.

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VUMC investigators find pathogens work together to infect host

Nov. 3, 2016—Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.

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Skaar receives American Asthma Foundation award

Aug. 6, 2015—Eric Skaar, Ph.D., MPH, the Ernest W. Goodpasture Professor of Pathology, has received a Scholar Award from the American Asthma Foundation (AAF).

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Physician-scientist is dream job for Vanderbilt’s Cassat

Dec. 4, 2014—Jim Cassat, M.D., Ph.D., a pediatric infectious disease specialist who joined the Vanderbilt faculty this summer, loves taking care of children with bone infections and doing research to understand the host-pathogen interactions during these invasive infections.

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Staph ‘gangs’ share nutrients during infection: study

Oct. 16, 2014—Antibiotic-resistant bacteria can share resources to cause chronic infections, Vanderbilt investigators have discovered. The findings shed light on a long-standing question in infectious diseases and may inform new treatment strategies.

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Dismantling staph’s drug resistance

Mar. 3, 2014—Targeting the enzyme FosB could make antibiotic-resistant staph bacteria sensitive to the antibiotic fosfomycin.

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Studies outline new model for staph bone infections

Jun. 20, 2013—Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.

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Antibacterial protein’s molecular workings revealed

Feb. 21, 2013—Vanderbilt investigators report new insights to the workings of calprotectin, an immune system protein that “starves” bacterial pathogens of the metal nutrients they require.

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Team creates new view of body’s infection response

Aug. 9, 2012—A new 3-D view of the body’s response to infection — and the ability to identify proteins involved in the response — could point to novel biomarkers and therapeutic agents for infectious diseases.

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Commonly prescribed antibiotic may not be best for kids’ MRSA

Aug. 15, 2011—Researchers at Vanderbilt find less commonly prescribed drug is more effective in treating MRSA skin infections in children.

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