Reporter
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An interacting factor in leukemia
A blood stem cell protein plays a role in the initiation and progression of leukemia, Vanderbilt researchers have found. Read MoreJan 25, 2021
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Inflammation in genetic epilepsy
Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments. Read MoreJan 21, 2021
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WIN for blocking cancer growth
William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth. Read MoreJan 21, 2021
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Mitochondrial stress and hypertension
Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential. Read MoreJan 12, 2021
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Microbial RNA and rheumatoid arthritis
Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases. Read MoreJan 11, 2021
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Vitamin D activation and cancer risk
Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women. Read MoreJan 7, 2021
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Building a cohort, the easy way
An automated system using keyword searches can help identify candidates for clinical trials on adverse drug reactions. Read MoreJan 7, 2021
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Health equity’s role in pandemic response crucial
In March, Vanderbilt University Medical Center leaders established a command center on campus to address the myriad issues that the Medical Center would face in the coming days, weeks and months as the COVID-19 pandemic encroached on Tennessee, then Nashville and finally on campus. Read MoreDec 16, 2020
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A deeper look at out-of-home care
Geographically targeted efforts to prevent children being placed in out-of-home care might be possible, Vanderbilt researchers report. Read MoreDec 15, 2020
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Polymer protection for heart muscle
Vanderbilt researchers demonstrate that the polymer P188 has promise as a therapy to prevent reperfusion injury — the cellular damage that occurs when blood flow returns after an ischemic event like a heart attack. Read MoreDec 14, 2020
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Model students: improving clinical decision-making
Vanderbilt investigators have devised a system to alert health IT teams to deteriorating performance in clinical prediction models. Read MoreDec 10, 2020
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Exploiting viral vulnerabilities
The isolation of human monoclonal antibodies against dangerous viruses including EEEV, Hendra and Nipah could offer new ways to treat and prevent these infections. Read MoreDec 10, 2020
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Study sheds light on diabetes and COVID interaction
COVID-19 has been linked to cases of new-onset diabetes, diabetes-related emergencies and a higher death rate among diabetes patients. Read MoreDec 10, 2020
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Study details early events of inflammatory response
Vanderbilt University Medical Center investigators have identified a key molecular player in the early events of the inflammatory response to infection. The findings suggest new therapeutic possibilities for enhancing the inflammatory response to protect against pathogens and for blocking inflammation gone awry in diseases like arthritis and atherosclerosis. Read MoreDec 10, 2020
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Nominations being sought for School of Medicine Faculty Awards
Nominations are being sought for the following 2021 Vanderbilt University School of Medicine Faculty Awards: Read MoreDec 10, 2020
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Vanderbilt University Medical Center’s Crowe receives 2020 “Golden Goose” Award for COVID-19 research
James Crowe Jr., MD, a physician-scientist at Vanderbilt University Medical Center who has pioneered development of human monoclonal antibodies as potential treatments for viral diseases, has won a 2020 “Golden Goose” Award. Read MoreDec 1, 2020
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Hot spots identified for colorectal cancer mortality rates among young women
Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology. Read MoreNov 23, 2020
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Why does COVID-19 seem to spare children? Vanderbilt University Medical Center study offers an answer
Researchers at Vanderbilt University Medical Center (VUMC) and their colleagues have determined a key factor as to why COVID-19 appears to infect and sicken adults and older people preferentially while seeming to spare younger children. Read MoreNov 18, 2020
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New drug for metastatic colorectal cancer enters phase 3 trial
A new therapy for metastatic colorectal cancer that has been granted fast track designation by the U.S. Food and Drug Administration is being tested in a phase 3 clinical trial at Vanderbilt-Ingram Cancer Center. Read MoreNov 18, 2020
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Statins to be studied for prevention of dementia, disability and heart disease
Vanderbilt University Medical Center (VUMC) researchers are enrolling adults aged 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease. Read MoreNov 17, 2020