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Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection. Read More

Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori. Read More

The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered. Read More

AstraZeneca is advancing into phase 3 clinical trials with an investigational COVID-19 therapy of two long-acting antibodies discovered by Vanderbilt University Medical Center and optimized by AstraZeneca. Read More

A computer-based method developed at Vanderbilt University Medical Center that scans electronic medical records (EMRs) for genetic contributors to disease has been used for the first time to reveal the impact of race on health. Read More

Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract. Read More

Conformational change in a reovirus surface protein modulate the virus’s attachment to host cells, Vanderbilt researchers have found. Read More

Vanderbilt researchers have identified a signaling pathway that promotes kidney fibrosis in patients with diabetes — and that could be targeted with an existing approved medication. Read More

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

Studies using large DNA biobanks revealed genetic variants associated with penicillin allergy, the most common type of drug-induced allergic reaction. Read More

Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of memory. Read More

Understanding immunity generated by smallpox vaccine may hold lessons for COVID-19 vaccine development. Read More

What users mention in online weight loss forum tracks with how much weight they lose. Read More

Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics. Read More

An international group of researchers including Vanderbilt epidemiologists has identified new DNA methylation biomarkers associated with prostate cancer risk. Read More

Eric Gamazon, PhD, assistant professor of Medicine, has been awarded a $1.5 million grant from the National Human Genome Research Institute, part of the National Institutes of Health (NIH), to develop novel computational tools that integrate functional genomic data and electronic health records. Read More

Angela Jefferson, PhD, professor of Neurology and director of the Vanderbilt Memory and Alzheimer’s Center, has been awarded a $3.7 million, three-year grant from the National Institute on Aging (NIA) to support establishment of a prospective NIA-funded Alzheimer’s Disease Research Center (ADRC) at Vanderbilt University Medical Center. Read More

Women with three or more uterine fibroids — non-cancerous growths — during pregnancy are more likely to have infants with reduced birthweight and may need additional surveillance. Read More

New findings demonstrate how genetic variations in the receptor that binds SARS-CoV-2 impact virus recognition and infectivity and offer insights to COVID-19 susceptibility and treatment. Read More