Psychosis

The microstructure of white matter in the brain could be an important risk marker for psychosis, Vanderbilt researchers have discovered. Read More

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis. Read More

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders. Read More

Inhibited temperament—a tendency to respond to novelty with wariness, fear or caution—may be a risk factor for schizophrenia that could be targeted for preventative interventions. Read More

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting. Read More

Functional magnetic resonance imaging has revealed faulty circuits between the thalamus – a central hub of brain activity – and other brain regions. Read More

When discovering drugs for brain disorders, it’s important to test the candidates in multiple ways to avoid advancing those with restricted physiological effects. Read More

Brain deficits are not present in the early stages of schizophrenia, suggesting it may be possible to delay or prevent the development of brain abnormalities. Read More

Bipolar depression and schizophrenia share patterns of changes in neurons that regulate information flow, new research shows. Read More