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pediatric surgery Archives

A new target for neuroblastoma

Feb. 14, 2018—Vanderbilt investigators have discovered that a sirtuin protein has oncogenic properties in neuroblastoma cells — and that blocking it reduces their growth and tumor-like characteristics.

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Boosting sarcoma cell death

Oct. 4, 2017—A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.

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Blocking neuroblastoma cell growth

Mar. 22, 2017—An inhibitor of cell metabolism may be a good therapeutic target for neuroblastoma, which accounts for about 15 percent of pediatric cancer-related deaths.

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Proliferative capacity of neuroblastoma

Aug. 31, 2016—The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.

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Changes in care improve recovery for surgery patients

Jul. 28, 2016—Many patients having surgeries at Monroe Carrell Jr. Children’s Hospital at Vanderbilt are experiencing better recoveries, with less opioids for pain, fewer post-surgery complications and shorter hospital stays due to the work of a medical team that has transformed the way surgeries are handled.

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Young girl’s road to recovery paved at Children’s Hospital

Nov. 20, 2014—When Kendra Kaufman walked into to a recent follow-up appointment with surgeon Dai Chung, M.D., the only help she needed to steady her steps came from ankle-foot-orthotics.

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Grant bolsters inguinal hernia repair research

Nov. 13, 2014—Martin Blakely, M.D., M.S., has been awarded a $3 million federal grant for a multi-center, multi-disciplinary study to examine the safety outcomes of early versus later inguinal hernia repair for premature infants.

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Exploring Wilms tumor race disparity

May. 29, 2014—Unique molecular "fingerprints" could explain the disparity in Wilms tumor incidence and point to novel, race-specific therapeutic targets.

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Factor CITED in pediatric liver cancer

Feb. 20, 2013—Vanderbilt researchers report that they have found a factor involved in the persistence of embryonic cells implicated in childhood liver cancer.

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Gates Foundation grant aids pediatric nutrition research

Jan. 24, 2013—Using a SmartPhone platform and a $100,000 grant from Grand Challenges Explorations, an initiative of the Bill & Melinda Gates Foundation, Vanderbilt Pediatric Surgeon John Pietsch, M.D., and fourth-year medical student Katherine Allen may revolutionize the way infants and children all over the world are assessed and treated for proper nutrition.

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Wilms’ tumors differ in developing nations

Apr. 13, 2012—In addition to limited health care resources, biological factors may play a role in the poor survival of children with a common kidney cancer in developing nations.

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