Pancreatic Cancer
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Research Snapshot: Researchers identify new cell subtype in early-stage pancreatic cancer
The lab of Kathy DelGiorno seeks to understand changes in the pancreas in response to injury and disease. In a recent project led by graduate student Leah Caplan, the lab investigated the formation of enteroendocrine cells throughout pancreatic tumor development. Read MoreJun 17, 2022
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Uncovering how injury to the pancreas impacts cancer formation
Research from scientists at the School of Medicine Basic Sciences and the Salk Institute for Biological Studies shows that cells in the pancreas form new cell types to mitigate injury but are then susceptible to cancerous mutations. Read MoreOct 29, 2021
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Pancreatic cancer clue
Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer. Read MoreAug 12, 2019
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Searching out pancreatic cancer risk
Vanderbilt researchers have identified a biomarker that could be used to predict pancreatic cancer risk. Read MoreDec 7, 2017
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Pancreatic cancer development
Elevated levels of the factor G-CSF appear to promote the development of aggressive pancreatic cancer, suggesting a new therapeutic approach for this devastating disease. Read MoreAug 31, 2017
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Metastatic pancreatic cancer ‘reprograms’ for malignancy
Metastatic pancreatic cancer — cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths — changes its metabolism and is “reprogrammed” for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics. Read MoreJan 19, 2017
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Chemo better option following pancreatic cancer surgery: study
A multicenter study led by Vanderbilt University Medical Center (VUMC) investigators found that pancreatic cancer patients who underwent surgery and received chemotherapy lived longer and had fewer cancer recurrences in other parts of the body than patients who also received chemoradiation therapy. Read MoreFeb 25, 2016
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Grant bolsters pancreatic cancer drug discovery efforts
The Lustgarten Foundation has awarded a $1.5 million Research Investigator Grant to Stephen Fesik, Ph.D., professor of Biochemistry, Pharmacology and Chemistry, for research designed to discover new drugs for the treatment of pancreatic cancer. Read MoreJan 29, 2015
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Pioneers of Discovery: Investigator seeks to debug cancer’s ‘bad software’
Beyond genetics — that’s the call Oliver McDonald, M.D., Ph.D., heard during the year between college and medical school he spent in a lab at St. Jude Children’s Research Hospital in Memphis. Read MoreJan 9, 2014
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Study helps define pancreatic cancer’s cellular origins
Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments. Read MoreJan 17, 2013
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Pancreas Center coordinates care for complex cases
Patients with pancreatic diseases can now access a team of multi-disciplinary specialists with one phone call to the new Vanderbilt Pancreas Center. Read MoreJan 10, 2013
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Musica’s nudes to wear purple for pancreatic cancer Nov. 1
(Image courtesy of Alan LeQuire) Nashville’s Musica statue will be bathed in purple light during the Paint Nashville Purple event for pancreatic cancer awareness at 6:30 p.m. Tuesday, Nov. 1, at the roundabout on Demonbreun Street. Linda’s Hope, a local nonprofit organization for pancreatic cancer awareness and… Read MoreOct 28, 2011