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Nucleic Acids Research Archives

Mitochondrial mutations and disease

Feb. 22, 2018—New findings suggest that oxidative stress damages mitochondrial DNA, and they link this damage to a disease state.

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Novel insights to antibiotic targets

Sep. 29, 2017—New mechanistic details about the DNA-unwinding activity of antibacterial protein targets could lead to the design of better antibiotic medicines.

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Bacterial resistance breaks bridges

Mar. 14, 2013—Understanding how bacteria become resistant to quinolone antibiotics could guide strategies for developing new antibacterial drugs.

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New view of DNA processing ‘hub’

Jan. 23, 2013—Structural studies reveal a new framework for understanding a central player in DNA processing.

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