NLM
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COVID-19 met with intensive teamwork
Team members serving COVID-19 inpatients were more densely connected, interacting far more than their medical ICU counterparts. Read MoreApr 1, 2021
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Gregor Mendel would be proud
A computational method that uses hospital billing codes and electronic health records can identify genetic disease cases before clinical teams do. Read MoreDec 12, 2019
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Getting the goods on obesity
Obesity and two post-operative complications linked with it have associated genetic variants in common, suggesting that obesity may be the culprit. Read MoreNov 19, 2019
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Intestinal immune cell interactions
Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases. Read MoreJul 30, 2019
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Analyzing single-cell landscapes
Qi Liu, PhD, Ken Lau, PhD, and colleagues have developed a new tool, sc-UniFrac, to quantify diverse cell types in single-cell studies. Read MoreNov 30, 2018
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“Idling” cancer cells may return
Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment. Read MoreApr 11, 2018
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Rheumatoid subtypes explored by PheWAS
A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis. Read MoreOct 7, 2016
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Data diving for health
To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases. Read MoreSep 23, 2015
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Drug signaling networks
Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action. Read MoreJul 15, 2015
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Protein “pockets” help ID cancer genes
Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response. Read MoreNov 11, 2014
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Drug discovery clues in network map
Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies. Read MoreAug 5, 2014
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Web tool speeds pulmonary hypertension discovery
The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis. Read MoreMar 5, 2014
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Molecular circuits in ovarian cancer
Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer. Read MoreNov 13, 2013
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Tool helps plumb electronic records
A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies. Read MoreAug 24, 2012