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NLM Archives

“Idling” cancer cells may return

Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.

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Rheumatoid subtypes explored by PheWAS

Oct. 7, 2016—A computer-based method pioneered at Vanderbilt is being used to compare subtypes of rheumatoid arthritis.

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Data diving for health

Sep. 23, 2015—To most effectively use electronic health records for research, investigators should query multiple components of the record to identify patients with specific diseases.

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Drug signaling networks

Jul. 15, 2015—Vanderbilt investigators have developed a new algorithm to understand the networks of signaling molecules that control drug action.

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Protein “pockets” help ID cancer genes

Nov. 11, 2014—Vanderbilt investigators have used a computational biology approach to uncover new cancer drivers and biomarkers of anticancer drug response.

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Drug discovery clues in network map

Aug. 5, 2014—Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies.

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Web tool speeds pulmonary hypertension discovery

Mar. 5, 2014—The pulmonary arterial hypertension knowledgebase (PAHKB), developed by Vanderbilt researchers, provides a useful tool for identifying PAH-related genes and signaling pathways relevant to pathogenesis.

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Molecular circuits in ovarian cancer

Nov. 13, 2013—Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

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Tool helps plumb electronic records

Aug. 24, 2012—A tool developed for one institution’s electronic health records can work at other institutions, potentially facilitating the use of these records in research studies.

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