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NIMH Archives

Forming memories through CaMKII

Dec. 19, 2017—Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory.

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Oxidative stress on the brain

Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.

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Researchers study unique couples intervention in Mozambique to reduce HIV transmission

Aug. 3, 2017—Researchers in the Vanderbilt Institute for Global Health are testing whether a unique “couples-centered” intervention developed in the southern African nation of Mozambique can reduce mother-to-child transmission of HIV.

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Regulating anxiety in the brain

Apr. 28, 2017—Two brain signaling pathways have overlapping functions in regulating anxiety, suggesting that therapeutics aimed at one or the other will impact both.

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Investigational new drug for Alzheimer’s scheduled for first study in humans

Dec. 27, 2016—Vanderbilt University scientists have received notification from the U.S. Food and Drug Administration that testing in humans may proceed for an investigational new drug for Alzheimer's disease after more than 10 years of research by scientists at Vanderbilt University and Vanderbilt University Medical Center.

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Reducing antidepressants’ side effects

Nov. 23, 2016—Vanderbilt investigators have discovered how antidepressant medicines that block serotonin uptake can increase bleeding risk.

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Blood exposures for traditional healers

Sep. 23, 2016—Traditional healers in sub-Saharan have a high rate of exposure to blood, putting them at risk for HIV and hepatitis C.

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Diabetes drugs may ease addiction

Jul. 18, 2016—Drugs that are being used clinically to treat obesity and diabetes may also have a role in treating drug abuse.

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COX-2 blocker could help PTSD

May. 12, 2016—COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.

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Putting schizophrenia to bed

Mar. 21, 2016—A new compound developed at Vanderbilt treats multiple symptoms of schizophrenia in an animal model, without causing sedation.

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Eye of a cytokine storm

Mar. 9, 2016—A new animal model can be used to “dissect” the inflammatory response to infection.

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Fat hormone’s role in zebrafish

Mar. 8, 2016—The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.

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