NIMH

Vanderbilt psychiatrists are probing brain circuit hyperactivity implicated in schizophrenia, with the idea that normalizing the hyperactivity may improve cognitive processes. Read More

Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report. Read More

Older depressed adults show accelerated brain aging, according to a new study from Vanderbilt researchers, who suggest that the effects of depression may speed the decline in cognitive functions in older individuals. Read More

Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment. Read More

The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found. Read More

Electronic health records and biobanks can be effectively combined to detect and study Mendelian diseases such as cystic fibrosis. Read More

Roger Colbran and colleagues have discovered new molecular details about the function of an enzyme with a key role in shaping learning and memory. Read More

An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms. Read More

Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy. Read More

Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis. Read More

Technology may be a viable option for reducing HIV risk for African Americans in rural communities, according to a new Vanderbilt report.  Read More

A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder. Read More

Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders. Read More

Inhibited temperament—a tendency to respond to novelty with wariness, fear or caution—may be a risk factor for schizophrenia that could be targeted for preventative interventions. Read More

A $3.4 million grant from the National Institute of Mental Health will fund Vanderbilt research on treatment resistance in patients with major depressive disorder and schizophrenia. Read More

Inhibiting COX-2 — an enzyme associated with inflammation — could provide a novel therapeutic approach for stress-related psychiatric disorders. Read More

A new Vanderbilt study examining stress in teens with and without autism spectrum disorder is now enrolling participants, thanks to a $2.3 million, five-year grant from the National Institute of Mental Health. Read More

There’s promise in specific immune system peptides—amino acid compounds that signal cells how to function. In this case, they may be affecting brain activity and, by extension, drug cravings. Read More

Brain imaging studies have implicated the connection between two brain regions in the pathophysiology of schizophrenia. Read More

Vanderbilt researchers have identified an interaction between two proteins that play a role in learning and memory. Read More