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Spying on shape-shifting enzyme

Mar. 18, 2011—New molecular views of an enzyme may inform therapies for neurological, psychiatric or cardiac diseases.

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Smell test tells disorders apart

Mar. 17, 2011—Patients with certain autonomic nervous system disorders have impaired odor identification, which could aid in diagnosis.

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New laser technique opens doors for drug discovery

Mar. 14, 2011—A new laser technique can measure interactions between proteins tangled in a cell's membrane and a variety of other biological molecules: extremely difficult measurements that can aid the process of drug discovery.

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Neuroscience drug discovery center opens at Vanderbilt

Mar. 11, 2011—Vanderbilt University Medical Center has established a new Center for Neuroscience Drug Discovery to accelerate research that may lead to new treatments for Parkinson's disease, schizophrenia and other disorders of the brain.

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Enzyme protects against inflamed colon

Mar. 7, 2011—Increasing an enzyme required for a type of colon tissue may help dampen inflammation, a known risk factor for colon cancer.

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Chasing Foxd3’s role in stem cells

Mar. 4, 2011—Researchers use genetic manipulations in mice and single-cell analyses to help explain stem cell regulation.

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Worm gene function? Check the map.

Mar. 3, 2011—New gene expression atlas created for roundworms provides a basis for establishing roles for individual genes in the development of specific cell types.

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A better picture of bone strength

Mar. 2, 2011—A component of some MRI scans reveals that "soft" components, like collagen and collagen-bound water, are important players in bone strength.

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New model to test how antidepressants work

Feb. 18, 2011—A new mouse model offers the ability to better test how selective serotonin reuptake inhibitors (SSRIs) work and could lead to the development of new classes of anti-depressants.

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Vanderbilt-pioneered fetal surgery procedure yields positive results

Feb. 9, 2011—Results of a landmark, seven-year National Institutes of Health-funded trial, Management of Myelomeningocele Study (MOMS), demonstrate clear benefit for babies who undergo fetal surgery to treat spina bifida, the most common birth defect in the central nervous system.

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Vanderbilt joins consortium to discover and map all Alzheimer’s genes

Feb. 1, 2011—Researchers at Vanderbilt University Medical Center, and across the globe, announced today a multi-national collaboration to discover and map all genes relating to Alzheimer’s disease through the formation of the International Genomics of Alzheimer’s Project (IGAP). Alzheimer’s disease, a progressive, neurodegenerative disorder that is fatal, has no cure and available drugs only marginally affect disease...

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Participants sought for study treating speech disorders in young children with cleft palate

Dec. 19, 2010—Young children born with cleft lip or palate are sought to participate in a groundbreaking intervention study to help improve their language and speech. The study, launched by Vanderbilt University and East Tennessee State University in January 2010, has already been found to have a positive impact on addressing speech disorders in these children.

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