NIGMS

Long live the therapeutic stem cells

May. 17, 2012—Enhancing stem cell survival is key to improving cell-based therapies for regenerative medicine, and a new drug could help.

Stem cell population may hold colon cancer clues

Mar. 29, 2012—Vanderbilt-Ingram Cancer Center researchers have identified a new population of intestinal stem cells that may hold clues to the origin of colorectal cancer.

Colon cancer’s cellular crossroads

Mar. 16, 2012—New information about signaling pathways involved in colorectal cancer could aid in assessing prognosis and identifying new therapeutic targets for the disease.

‘Detangler’ binds, bends and cuts DNA

Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.

Studies pinpoint new anti-cancer drug target

Feb. 23, 2012—Vanderbilt researchers have discovered a new molecular participant in the Wnt signaling pathway, which plays important roles in cell growth, development and cancer.

On the tail of RSV infection mechanism

Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.

Nicotine may aid memory for some older adults: study

Jan. 13, 2012—Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published this week by Paul Newhouse, director of the Center for Cognitive Medicine.

Meds’ benefits differ in dialysis patients

Jan. 5, 2012—About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to selecting medication for heart disease...