NIGMS
‘Detangler’ binds, bends and cuts DNA
Mar. 2, 2012—New details on the DNA-cutting activity of topoisomerase II, a target of anti-cancer drugs, could lead to better chemotherapeutic agents.
Studies pinpoint new anti-cancer drug target
Feb. 23, 2012—Vanderbilt researchers have discovered a new molecular participant in the Wnt signaling pathway, which plays important roles in cell growth, development and cancer.
On the tail of RSV infection mechanism
Feb. 15, 2012—New details about the life cycle of respiratory syncytial virus (RSV) could aid the development of therapies to combat this leading cause of serious illness in infants and the elderly.
Nicotine may aid memory for some older adults: study
Jan. 13, 2012—Wearing a nicotine patch may help improve memory loss in older adults with mild cognitive impairment, according to a study published this week by Paul Newhouse, director of the Center for Cognitive Medicine.
Meds’ benefits differ in dialysis patients
Jan. 5, 2012—About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to selecting medication for heart disease...
Divvying up chromosomes
Dec. 15, 2011—Protein helps ensure proper division of chromosomes during cell division.
Virus-linked cancer gets help from host
Dec. 15, 2011—Host cell protein may be a target for strategies to limit spread of virus-induced squamous cell cancers.
Drug target for deadly heart infection
Dec. 1, 2011—Structural biology studies of a bacterial protein suggest a new target for treating life-threatening heart infection.
Let there be light and melatonin
Nov. 4, 2011—Light and the hormone melatonin may play important roles in the developing brain.
Heart protein may be target for colon cancer therapies
Oct. 7, 2011—A protein critical in heart development may also play a part in colon cancer progression.
Study puts a new spin on ibuprofen’s actions
Sep. 29, 2011—Vanderbilt University investigators have discovered surprising new insights into the actions of NSAIDs.
Starvation diet kills staph bacteria
Aug. 26, 2011—The antibiotics of the future could take a page from the immune system’s playbook – and “starve” bacteria of the nutrients they need.