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NIDDK

‘Longevity’ gene aids kidney survival

Apr. 17, 2013—A gene associated with cell survival and longevity may protect the kidney from acute injury.

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“Silent” B cells trigger autoimmunity

Apr. 3, 2013—Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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Plant compound stops colon cancer cells

Mar. 29, 2013—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

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IRF6 on the tip of tongue development

Mar. 18, 2013—The factor IRF6 plays important roles in the development of the tongue.

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Target for inflammatory bowel disease

Mar. 1, 2013—The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

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Pancreas cells full of potential

Feb. 18, 2013—Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

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Linking oxygen, iron and red blood cells

Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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Study helps define pancreatic cancer’s cellular origins

Jan. 17, 2013—Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments.

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Cancer markers from archived tissue

Dec. 20, 2012—Archived tissue samples are yielding new disease biomarkers.

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Bird’s eye view of gut development

Nov. 19, 2012—A new map of the developing gut of quail offers valuable tool for studying intestinal diseases.

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