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NIDDK

Salt revs stomach bug’s cancer impact

May. 13, 2013—A high-salt diet worsens the carcinogenic effects of Helicobacter pylori, a bacterium that colonizes the stomachs of half of the world’s population.

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Dual-action enzyme protects esophagus

May. 9, 2013—An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus.

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Food variety drives overeating in mouse model of obesity syndrome

Apr. 25, 2013—Dietary variety – not high-fat or sugary foods – appears to stimulate overeating in a mouse model of an inherited obesity syndrome.

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‘Longevity’ gene aids kidney survival

Apr. 17, 2013—A gene associated with cell survival and longevity may protect the kidney from acute injury.

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“Silent” B cells trigger autoimmunity

Apr. 3, 2013—Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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Plant compound stops colon cancer cells

Mar. 29, 2013—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be useful in colon cancer therapy.

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IRF6 on the tip of tongue development

Mar. 18, 2013—The factor IRF6 plays important roles in the development of the tongue.

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Target for inflammatory bowel disease

Mar. 1, 2013—The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

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Pancreas cells full of potential

Feb. 18, 2013—Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

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Linking oxygen, iron and red blood cells

Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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