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NIDDK

Pancreas cells full of potential

Feb. 18, 2013—Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

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Linking oxygen, iron and red blood cells

Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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HDL cholesterol impaired in kidney disease

Jan. 21, 2013—HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

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Study helps define pancreatic cancer’s cellular origins

Jan. 17, 2013—Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments.

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Cancer markers from archived tissue

Dec. 20, 2012—Archived tissue samples are yielding new disease biomarkers.

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Bird’s eye view of gut development

Nov. 19, 2012—A new map of the developing gut of quail offers valuable tool for studying intestinal diseases.

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Stomach bug alters tumor suppressor

Oct. 23, 2012—The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

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Setting traps to probe gene function

Oct. 18, 2012—A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.

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How ‘Jedi’ disposes of dead neurons

Sep. 19, 2012—The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.

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Enzyme counters stomach acid attack

Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.

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Ancestry impacts smoking risk for lungs

Aug. 7, 2012—Smoking is more detrimental to lung function in individuals with high proportions of African ancestry.

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