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nida Archives

Immune system emerges as partner in opioid cravings fight

Sep. 5, 2018—There’s promise in specific immune system peptides—amino acid compounds that signal cells how to function. In this case, they may be affecting brain activity and, by extension, drug cravings.

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Investigators find that bile acids reduce cocaine reward

Aug. 30, 2018—The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction.

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Shaping reward circuits

May. 18, 2018—Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry.

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An immune regulator of addiction

Aug. 4, 2017—Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

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Patrick honored for neonatal abstinence syndrome research

Jun. 15, 2017—Stephen W. Patrick, M.D., MPH, MS, has been chosen to receive the Nemours Child Health Services Research Award, recognizing his work surrounding neonatal abstinence syndrome, a drug withdrawal syndrome experienced by infants exposed to opioids while in utero.

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Diabetes drugs may ease addiction

Jul. 18, 2016—Drugs that are being used clinically to treat obesity and diabetes may also have a role in treating drug abuse.

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Drug monitoring programs reduce opioid deaths: study

Jun. 23, 2016—The implementation of state prescription drug monitoring programs was associated with the prevention of approximately one opioid-related overdose death every two hours on average nationwide, according to a new Vanderbilt-led study released this week in the journal "Health Affairs."

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New pain medicine from a fungus?

May. 13, 2016—Collybolide – a natural product isolated from a mushroom – is a promising candidate for the development of non-addictive pain medicines.

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New role identified for p73 gene

Apr. 1, 2016—The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.

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New view of dopamine heteromers

Jan. 23, 2015—Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

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Reversing stress-induced anxiety

Jul. 21, 2014—Augmenting the signals of natural “endocannabinoids” in the brain may be a promising approach for treating mood and anxiety disorders.

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New view of neurotransmitter transport

Apr. 24, 2014—Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders.

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