Aug. 24, 2020—Surgical patients are being given more opioids than they need for postsurgical pain management, raising the risk of addiction.
Apr. 8, 2020—Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders.
Dec. 17, 2019—A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.
Jul. 24, 2019—A first-of-its-kind mouse model may help reveal mechanistic underpinnings for the altered behaviors of autism spectrum disorder.
Feb. 15, 2019—Danny Winder and colleagues have demonstrated how norepinephrine and a stress factor call CRF interact, which may lead to new treatments for stress-related disorders.
Sep. 5, 2018—There’s promise in specific immune system peptides—amino acid compounds that signal cells how to function. In this case, they may be affecting brain activity and, by extension, drug cravings.
Aug. 30, 2018—The discovery that high levels of bile acids appear to blunt cravings for cocaine could lead to new treatments for addiction.
May. 18, 2018—Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry.
Aug. 4, 2017—Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.
Jun. 15, 2017—Stephen W. Patrick, M.D., MPH, MS, has been chosen to receive the Nemours Child Health Services Research Award, recognizing his work surrounding neonatal abstinence syndrome, a drug withdrawal syndrome experienced by infants exposed to opioids while in utero.
Jul. 18, 2016—Drugs that are being used clinically to treat obesity and diabetes may also have a role in treating drug abuse.
Jun. 23, 2016—The implementation of state prescription drug monitoring programs was associated with the prevention of approximately one opioid-related overdose death every two hours on average nationwide, according to a new Vanderbilt-led study released this week in the journal "Health Affairs."