New England Journal Of Medicine

Sedative medications used in intensive care are associated with increased delirium, which is in turn connected with higher medical costs and greater risk of death and ICU-related dementia. Read More

An experimental coronavirus vaccine stimulated robust immune responses against SARS-CoV-2, the virus that causes COVID-19, and raised no serious safety concerns in an early-stage clinical trial. Read More

A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25%, according to a VUMC study. Read More

Scarcely a year after its national launch, the “All of Us” research program, which aims to accelerate the prevention and treatment of disease, has enrolled more than 230,000 research participants — more than a fifth of its recruitment goal of 1 million people. All Read More

New research indicates the time window for a thrombectomy following a stroke is longer than previously thought, but how soon the surgery occurs still matters. Read More

Vanderbilt University Medical Center is encouraging its medical providers to stop using saline as intravenous fluid therapy for most patients, a change provoked by two companion landmark studies released Feb. 27 that are anticipated to improve survival and decrease kidney complications. Read More

A new clinical trial by investigators at Vanderbilt University Medical Center (VUMC) and other leading medical centers found that an intensive transplant treatment using the patient’s own stem cells can improve survival and quality of life for patients with advanced scleroderma. Read More

Healthcare is more than diagnosing and treating disease. To truly improve health outcomes for individuals and communities, the mental, behavioral and social determinants of health must be fully integrated with physical factors at all levels of the healthcare system. Read More

An effort at Vanderbilt University Medical Center (VUMC) to enhance clinical decision making through cross-departmental collaboration and effective use of diagnostics has improved patient care and saved the institution more than $1 million in 2016, VUMC officials reported this week. Read More

New multicenter research that includes Vanderbilt University Medical Center (VUMC) investigators, could change treatment approaches to simple skin abscesses, infections often caused by Staphylococcus aureus (staph) bacteria. Read More

This week Douglas Heimburger, M.D., M.S., professor of Medicine at Vanderbilt, joined a growing chorus calling for preservation of the Fogarty International Center of the National Institutes of Health (NIH). Read More

Social risk factors including income, education and ethnic background influence health outcomes and should be taken into account in Medicare payment models, according to a New England Journal of Medicine “Perspective” titled “Social Risk Factors and Equity in Medicare Payment.” Read More

The researchers examine whether the financial struggles of some major insurers under the Affordable Care Act reflect a policy failure or a mismatch of these firms’ capabilities and strategies to a newly created market. Read More

Using patient outcomes data from approximately 1,800 hospitals, the largest demonstration to date of automated safety surveillance of a medical device is reported in this week’s New England Journal of Medicine. Read More

Justin Balko, Pharm.D., Ph.D., seated, Javid Moslehi, M.D., left, and Douglas Johnson, M.D., MSCI, review data on rare cardiac side effects linked to cancer immunotherapy combination therapy. (photo by Susan Urmy) Combination therapy using two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side… Read More

Improved therapies have led to a spike in the number of people living with cancer, and today there are more than 15.5 million survivors in the United States. However, some of these therapies can cause toxicities to the heart, the vessels and the body’s metabolism. Read More

New ethical rules for scientists who do experiments involving human beings are about to kick in. It's the first update in more than 40 years. Read More

Reduced-nicotine cigarettes were beneficial in reducing nicotine exposure and dependence, and also the number of cigarettes smoked per day, when compared with standard-nicotine cigarettes in a six-week study published in the New England Journal of Medicine. Read More

Anti-cancer drugs are typically tested on one type of cancer at a time. But an international consortium of cancer investigators, including Vanderbilt-Ingram Cancer Center (VICC) researchers, simultaneously tested an existing therapy in patients with several different forms of cancer that all exhibit the same tumor gene mutation. Read More

Vanderbilt-Ingram Cancer Center (VICC) investigators and colleagues at several major medical centers have been testing a new targeted therapy that is showing promise for the treatment of a rare tumor that forms in and around joint cavities. Read More