Neurotransmitter
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Research Snapshot: Protons can tune synaptic signaling by changing the shape of a protein receptor
Research from Teru Nakagawa, professor of molecular physiology and biophysics, describes intricacies of normal brain function with implications for our understanding of brain injury and recovery: A decrease in pH can modify a neurotransmitter receptor’s structure, thereby modulating its location and kinetics. Read MoreAug 14, 2024
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Research Snapshot: Researchers demonstrate that dopamine is involved in novelty-based learning
Vanderbilt researchers in the lab of Erin Calipari, assistant professor of pharmacology and molecular physiology and biophysics, have demonstrated a role for dopamine signaling in novelty-based learning—a finding that could have major impacts on how neurological diseases are treated. Read MoreDec 16, 2022
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Vanderbilt neuroscientists uncover a novel means of interneuronal communication using extracellular vesicles
By studying extracellular vesicles from the brain, researchers at Vanderbilt and Argentina’s Universidad Nacional de Córdoba are the first to show how the incorporation of extracellular proteins into a neuron can modify neurotransmission Read MoreMay 24, 2021
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New view of transporter dynamics
New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants. Read MoreOct 23, 2014
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New view of neurotransmitter transport
Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders. Read MoreApr 24, 2014
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Neurotransmitter’s role in bone balance
Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling. Read MoreNov 7, 2013
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New clue to ADHD
A rare genetic change adds support to the idea that altered dopamine signaling is a key risk factor for ADHD. Read MoreMay 15, 2012