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NCATS Archives

Low prenatal alcohol’s brain impact

Dec. 21, 2012—Even relatively low levels of in utero alcohol exposure impact fetal brain development, and the effects last into adulthood, study finds.

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Inherited lung disease no worse in offspring

Nov. 15, 2012—An inherited lung disease does not appear to have earlier onset and increased severity – a phenomenon called genetic anticipation – in successive generations.

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Kidney woes during heart failure

Nov. 8, 2012—Levels of the protein NGAL may be a good predictor of worsening kidney function in patients with acute heart failure.

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Bacterial signals in sarcoidosis

Nov. 6, 2012—Study adds evidence for infectious agents’ role in sarcoidosis, an inflammatory condition that can lead to respiratory failure and death.

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Toxin provides endometriosis clues

Nov. 2, 2012—Environmental toxins may contribute to endometriosis-related infertility by disrupting endometrial response to progesterone.

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More gene links to breast cancer risk

Oct. 19, 2012—Two newly identified gene variants linked to breast cancer may aid in predicting disease risk and targeting screening and prevention strategies.

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Cell entry ports for cold virus

Sep. 25, 2012—The respiratory virus HMPV uses its fusion (F) protein – which interacts with cellular receptors called integrins – to bind to and enter target cells.

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Parkinson’s therapy may impact language

Sep. 7, 2012—Deep brain stimulation used to treat Parkinson’s disease may impair some aspects of language processing, a recent study suggests.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Vanderbilt-led team to develop ‘microbrain’ to improve drug testing

Jul. 24, 2012—Creating a device out of human cells that simulates brain chemistry is the goal of a $6.4 million grant which is part of major new federal initiative to develop a series of “organs on a chip” designed to improve the drug development process.

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Long antibodies better against HIV

Jul. 19, 2012—Understanding how antibodies with long “loops” form may be important for HIV vaccine development.

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VU study finds stress fuels breast cancer metastasis to bone

Jul. 18, 2012—Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

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